Phần 3: Nghiên cứu bệnh lý đơn bào ở người chưa được quan tâm đúng mực về phương diện bệnh tiêu hóa
Bất kỳ nhiễm trùng đơn bào nào cũng có thể không biểu hiện triệu chứng hoặc rất nhẹ trên cá nhân bình thường, nhưng có thể đe dọa tính mạng trên các bệnh nhân suy giảm miễn dịch, đặc biệt trên các bệnh nhân HIV/AIDS). Bằng chứng cho thấy nhiều người khỏe mạnh là nơi “che dấu”một số lượng nhỏ Pneumocystis carinii trong phổi của họ. Song, tác nhân này lại là mối đe dọa tử vong do viêm phổi trên các bệnh nhân HIV/AIDS. Toxoplasma gondii, một loại đơn bào thường gặp, thường gây bệnh nhẹ sau thời gian nhiễm trùng tiềm tàng kéo dài.
Tuy nhiên, trên bệnh nhân HIV/AIDS thì ký sinh trùng này có thể gây tử vong do viêm não. Cryptosporidium được mô tả vào thế kỷ 19, nhưng nhiễm trùng ở người lan rộng chỉ được nhận ra trong thời gian gần đây. Cryptosporidium là một loại đơn bào có thể dẫn đến nhiều biến chứng nghiêm trọng trên bệnh nhân HIV/AIDS.
Evaluation of the C-Terminal Fragment of Entamoeba histolytica Gal/GalNAc Lectin Intermediate Subunit as a Vaccine Candidate against Amebic Liver Abscess.
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Innate immunity prevents tissue invasion by Entamoeba histolytica.
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Laboratory diagnosis of amebiasis in a sample of students from southeastern Brazil and a comparison of microscopy with enzyme-linked immunosorbent assay for screening of infections with Entamoeba sp.
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Comparison of a stool antigen detection kit and PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar infections in asymptomatic cyst passers in Iran.
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High prevalence rate of Entamoeba histolytica asymptomatic infection in a rural Mexican community.
Ramos F, Morán P, González E, García G, Ramiro M, Gómez A, DE León Mdel C, Melendro EI, Valadez A, Ximénez C.
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Comparison between R-phycocyanin-labeled and R-phycoerythrin-labeled monoclonal antibody (Mab) probes for the detection of Entamoeba histolytica trophozoites.
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Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh.
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Host immune response to intestinal amebiasis.
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PLoS Pathog . 2013;9(8):e1003489. doi: 10.1371/journal.ppat.1003489. Epub 2013 Aug 22. Review. No abstract available.
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Proteomic identification of S-nitrosylated proteins in the parasite Entamoeba histolytica by resin-assisted capture: insights into the regulation of the Gal/GalNAc lectin by nitric oxide.
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Amoebiasis vaccine development: A snapshot on E. histolytica with emphasis on perspectives of Gal/GalNAc lectin.
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A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children.
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Sahara K, Hori W, Masuda T, Ohata K, Yamazaki F, Akahane S, Hattori H, Yuasa H, Hashizume I, Tanaka Y, Nagakura K, Tachibana H.
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Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis.
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Crosstalk at the initial encounter: interplay between host defense and ameba survival strategies.
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Leptin receptor mutation results in defective neutrophil recruitment to the colon during Entamoeba histolytica infection.
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MBio . 2014 Dec 16;5(6). pii: e02046-14. doi: 10.1128/mBio.02046-14.
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[INCIDENCE OF ENTAMOEBA HISTOLYTICA IN 800 COPROLOGIC EXAMINATIONS DONE IN THE 5 YEAR PERIOD 1956-61 AT THE CLINICA MEDICA OF PALERMO].
BALSANO F, MANSUETO S.
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Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis.
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Allason-Jones E, Mindel A, Sargeaunt P, Katz D.
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