Trong tiến trình tiến tới phòng chống & loại trừ sốt rét trên thế giới cũng như tại Việt Nam, trong đó không kể đến việc loại trừ loài ký sinh trùng có chu kỳ sinh học và phát triển đặc biệt là Plasmodium vivax, vì khó khăn trong diệt trừ thể ẩn hay thể ngủ trong gan. Hơn nữa, theo khuyến cáo của Tổ chức Y tế thế giới và Bộ Y tế Việt Nam là phải dùng liệu trình dài 14 ngày của thuốc primaquine phosphate để diệt giao bào chống lây lan và diệt thể ẩn chống tái phát xa, nhằm tiến tới loại trừ sốt rét tốt nhất.

Tuy nhiên, khi áp dụng liệu trình dài ngày như vậy, không những khó đạt được sự chấp thuận và tuân thủ dùng thuốc của bệnh nhân sốt rét mà còn có thể có nguy cơ gây tán huyết trên các bệnh nhân vốn dĩ có cơ địa thiếu men G6PD. Do vậy, trong thời gian đến nếu việc nghiên cứu thuốc Tafenoquine có kết quả tốt, có thể đưa vào điều trị như một thuốc thay thế cho primaquine phosphate. Các nghiên cứu từ năm 1974 đến 2017 đã được cập nhật và công bố được chia sẻ dưới đây:

Glucose-6-phosphate dehydrogenase deficiency and malaria: cytochemical detection of heterozygous G6PD deficiency in women.

Peters AL, Van Noorden CJ.

J Histochem Cytochem. 2009 Nov;57(11):1003-11. doi: 10.1369/jhc.2009.953828. Epub 2009 Jun 22. Review.

PMID: 19546473 Free PMC Article Similar articles Select item 161393392.

Biochemical and cytochemical evaluation of heterozygote individuals with glucose-6-phosphate dehydrogenase deficiency.

Gurbuz N, Aksu TA, Van Noorden CJ.

Acta Histochem. 2005;107(4):261-7. Epub 2005 Sep 1.

PMID: 16139339 Similar articles Select item 239650283.

Evaluation of the phenotypic test and genetic analysis in the detection of glucose-6-phosphate dehydrogenase deficiency.

Nantakomol D, Paul R, Palasuwan A, Day NP, White NJ, Imwong M.

Malar J. 2013 Aug 21;12:289. doi: 10.1186/1475-2875-12-289.

PMID: 23965028 Free PMC Article Similar articles Select item 239618744.

Cryopreservation of glucose-6-phosphate dehydrogenase activity inside red blood cells: developing a specimen repository in support of development and evaluation of glucose-6-phosphate dehydrogenase deficiency tests.

Kahn M, LaRue N, Bansil P, Kalnoky M, McGray S, Domingo GJ.

Malar J. 2013 Aug 20;12:286. doi: 10.1186/1475-2875-12-286.

PMID: 23961874 Free PMC Article Similar articles Select item 24722365.

Comparison between the chromate inhibition test and a cytochemical method for the determination of glucose-6-phosphate dehydrogenase deficiency in erythrocytes.

Jonges GN, Hagen H, Van Noorden CJ, Weening RS, Roos D.

Clin Chim Acta. 1989 May 15;181(2):135-41.

PMID: 2472236 Similar articles Select item 215013926.

Modification to reporting of qualitative fluorescent spot test results improves detection of glucose-6-phosphate dehydrogenase (G6PD)-deficient heterozygote female newborns.

Nadarajan V, Shanmugam H, Sthaneshwar P, Jayaranee S, Sultan KS, Ang C, Arumugam S.

Int J Lab Hematol. 2011 Oct;33(5):463-70. doi: 10.1111/j.1751-553X.2011.01309.x. Epub 2011 Apr 19.

PMID: 21501392 Similar articles Select item 197896507.

Hình 1

Impact of the method of G6PD deficiency assessment o­n genetic association studies of malaria susceptibility.

Johnson MK, Clark TD, Njama-Meya D, Rosenthal PJ, Parikh S.

PLoS o­ne. 2009 Sep 30;4(9):e7246. doi: 10.1371/journal.pone.0007246.

PMID: 19789650 Free PMC ArticleSimilar articles Select item 250710038.

Comparison of quantitative and qualitative tests for glucose-6-phosphate dehydrogenase deficiency.

LaRue N, Kahn M, Murray M, Leader BT, Bansil P, McGray S, Kalnoky M, Zhang H, Huang H, Jiang H, Domingo GJ.

Am J Trop Med Hyg. 2014 Oct;91(4):854-61. doi: 10.4269/ajtmh.14-0194. Epub 2014 Jul 28.

PMID: 25071003 Free PMC Article Similar articles Select item 173551699.

X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria.

Guindo A, Fairhurst RM, Doumbo OK, Wellems TE, Diallo DA.

PLoS Med. 2007 Mar;4(3):e66.

PMID: 17355169 Free PMC Article Similar articles Select item 2184908110.

Hình 2

Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials.

Carter N, Pamba A, Duparc S, Waitumbi JN.

Malar J. 2011 Aug 17;10:241. doi: 10.1186/1475-2875-10-241.

PMID: 21849081 Free PMC Article Similar articles Select item 355207811.

Glucose-6-phosphate dehydrogenase of malaria parasite Plasmodium falciparum.

Yoshida A, Roth EF Jr.

Blood. 1987 May;69(5):1528-30.

PMID: 3552078 Free Article Similar articles Select item 2668604512.

Hình 3

Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study.

Uyoga S, Ndila CM, Macharia AW, Nyutu G, Shah S, Peshu N, Clarke GM, Kwiatkowski DP, Rockett KA, Williams TN; MalariaGEN Consortium.

Lancet Haematol. 2015 Oct;2(10):e437-44. doi: 10.1016/S2352-3026(15)00152-0. Epub 2015 Sep 22.

PMID: 26686045 Free PMC ArticleSimilar articles Select item 276880513.

Flow cytofluorometric analysis of enzyme reactions based o­n quenching of fluorescence by the final reaction product: detection of glucose-6-phosphate dehydrogenase deficiency in human erythrocytes.

Van Noorden CJ, Dolbeare F, Aten J.

J Histochem Cytochem. 1989 Sep;37(9):1313-8.

PMID: 2768805 Similar articles Select item 2890253214.

Comparison of Spectrophotometry, Chromate Inhibition, and Cytofluorometry Versus Gene Sequencing for Detection of Heterozygously Glucose-6-Phosphate Dehydrogenase-Deficient Females.

Peters AL, Veldthuis M, van Leeuwen K, Bossuyt PMM, Vlaar APJ, van Bruggen R, de Korte D, Van Noorden CJF, van Zwieten R.

J Histochem Cytochem. 2017 Nov;65(11):627-636. doi: 10.1369/0022155417730021. Epub 2017 Sep 13.

PMID: 28902532 Similar articles Select item 682165415.

Hình 4

Neonatal hyperbilirubinaemia in heterozygous glucose-6-phosphate dehydrogenase deficient females.

Meloni T, Forteleoni G, Dore A, Cutillo S.

Br J Haematol. 1983 Feb;53(2):241-6.

PMID: 6821654 Similar articles Select item 367741216.

Detection of glucose-6-phosphate dehydrogenase deficiency in erythrocytes: a spectrophotometric assay and a fluorescent spot test compared with a cytochemical method.

Wolf BH, Weening RS, Schutgens RB, van Noorden CJ, Vogels IM, Nagelkerke NJ.

Clin Chim Acta. 1987 Sep 30;168(2):129-36.

PMID: 3677412 Similar articles Select item 2732947117.

Glucose-6-phosphate dehydrogenase deficiency among Yemeni children residing in malaria-endemic areas of Hodeidah governorate and evaluation of a rapid diagnostic test for its detection.

Abdul-Ghani R, Mahdy MA, Saif-Ali R, Alkubati SA, Alqubaty AR, Al-Mikhlafy AA, Al-Eryani SM, Al-Mekhlafi AM, Alhaj A.

Malar J. 2016 Jun 21;15:327. doi: 10.1186/s12936-016-1372-9.

PMID: 27329471 Free PMC Article Similar articles Select item 240865418.

A sensitive cytochemical staining method for glucose-6-phosphate dehydrogenase activity in individual erythrocytes. II. Further improvements of the staining procedure and some observations with glucose-6-phosphate dehydrogenase deficiency.

Van Noorden CJ, Vogels IM.

Br J Haematol. 1985 May;60(1):57-63.

PMID: 2408654 Similar articles Select item 2368007119.

Hình 5

Determination of optimal cutoff value to accurately identify glucose-6-phosphate dehydrogenase-deficient heterozygous female neonates.

Miao JK, Chen QX, Bao LM, Huang Y, Zhang J, Wan KX, Yi J, Wang SY, Zou L, Li TY.

Clin Chim Acta. 2013 Sep 23;424:131-5. doi: 10.1016/j.cca.2013.05.004. Epub 2013 May 13.

PMID:23680071 Similar articles Select item 974679420.

Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum may explain malaria protection in G6PD deficiency.

Cappadoro M, Giribaldi G, O'Brien E, Turrini F, Mannu F, Ulliers D, Simula G, Luzzatto L, Arese P.

Blood. 1998 Oct 1;92(7):2527-34.

PMID: 9746794 Free Article Similar articles

Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers.

Rueangweerayut R, Bancone G, Harrell EJ, Beelen AP, Kongpatanakul S, Möhrle JJ, Rousell V, Mohamed K, Qureshi A, Narayan S, Yubon N, Miller A, Nosten FH, Luzzatto L, Duparc S, Kleim JP, Green JA.

Am J Trop Med Hyg. 2017 Sep;97(3):702-711. doi: 10.4269/ajtmh.16-0779. Epub 2017 Jul 27.

PMID: 28749773 Free PMC Article Similar articles Select item 1074727122.

Red cell glucose-6-phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population.

May J, Meyer CG, Grossterlinden L, Ademowo OG, Mockenhaupt FP, Olumese PE, Falusi AG, Luzzatto L, Bienzle U.

Trop Med Int Health. 2000 Feb;5(2):119-23.

PMID: 10747271 Free Article Similar articles Select item 394282823.

Hình 6

Excess release of ferriheme in G6PD-deficient erythrocytes: possible cause of hemolysis and resistance to malaria.

Janney SK, Joist JJ, Fitch CD.

Blood. 1986 Feb;67(2):331-3.

PMID: 3942828 Free Article Similar articles Select item 2035028524.

Discussion o­n pharmacogenetic interaction in G6PD deficiency and methods to identify potential hemolytic drugs.

Manganelli G, Fico A, Martini G, Filosa S.

Cardiovasc Hematol Disord Drug Targets. 2010 Jun;10(2):143-50. Review.

PMID: 20350285 Similar articles Select item 876132025.

Enhanced vesiculation exacerbates complement-dependent hemolysis in glucose-6-phosphate dehydrogenase deficient red blood cells.

Tsai KJ, Shih LY, Hung IJ, Huang SW, Wei JS, Liu TZ, Chiu DT.

Life Sci. 1996;59(10):867-76.

PMID: 8761320 Similar articles Select item 1633761826.

Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency.

Tagarelli A, Piro A, Bastone L, Condino F, Tagarelli G.

Clin Biochem. 2006 Feb;39(2):183-6. Epub 2005 Dec 7.

PMID: 16337618 Similar articles Select item 152348127.

Hình 7

Erythrocyte glucose-6-phosphate dehydrogenase and pyruvate kinase activities in hemoglobin H disease.

Kuptamethi S, Tantiniti P, Wanachiwanawin W, Fucharoen S, Thareeruchata S, Choopanya K.

Southeast Asian J Trop Med Public Health. 1992 Mar;23(1):64-70.

PMID: 1523481 Similar articles Select item 564630328.

A tetrazolium-linked cytochemical method for estimation of glucose-6-phosphate dehydrogenase activity in individual erythrocytes: applications in the study of heterozygotes for glucose-6-phosphate dehydrogenase deficiency.

Fairbanks VF, Lampe LT.

Blood. 1968 May;31(5):589-603. No abstract available.

PMID: 5646303 Free Article Similar articles Select item 268777629.

Hình 8

Susceptibility to hydrogen peroxide of Plasmodium falciparum infecting glucose-6-phosphate dehydrogenase-deficient erythrocytes.

Kamchonwongpaisan S, Bunyaratvej A, Wanachiwanawin W, Yuthavong Y.

Parasitology. 1989 Oct;99 Pt 2:171-4.

PMID: 2687776 Similar articles Select item 2625113930.

[Glucose-6-phosphate dehydrogenase deficiency in Japan].

Kanno H, Ogura H.

Rinsho Ketsueki. 2015 Jul;56(7):771-7. doi: 10.11406/rinketsu.56.771. Japanese.

PMID: 26251139 Similar articles Select item 2577146731.

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in southeast Iran: implications for malaria elimination.

Tabatabaei SM, Salimi Khorashad A, Sakeni M, Raeisi A, Metanat Z.

J Infect Dev Ctries. 2015 Mar 15;9(3):289-97. doi: 10.3855/jidc.5572.

PMID: 25771467 Free Article Similar articles Select item 2461512832.

G6PD A- deficiency and severe malaria in The Gambia: heterozygote advantage and possible homozygote disadvantage.

Sirugo G, Predazzi IM, Bartlett J, Tacconelli A, Walther M, Williams SM.

Am J Trop Med Hyg. 2014 May;90(5):856-9. doi: 10.4269/ajtmh.13-0622. Epub 2014 Mar 10.

PMID: 24615128 Free PMC Article Similar articles Select item 204946833.

Hình 9

Heterozygous pyruvate kinase deficiency and severe hemolytic anemia in a pregnant woman with concomitant, glucose-6-phosphate dehydrogenase deficiency.

Vives Corrons JL, García AM, Sosa AM, Pujades A, Colomer D, Linares M.

Ann Hematol. 1991 May;62(5):190-3.

PMID: 2049468 Similar articles Select item 1159353734.

A diagnostic kit to screen individuals with glucose-6-phosphate dehydrogenase defect and its application o­n anti-malaria spot in the countryside.

Nie C, Zhao S.

Chin Med J (Engl). 1999 Apr;112(4):349-51.

PMID: 11593537 Similar articles Select item 378741535.

[Cytochemical study of erythrocyte glucose-6-phosphate dehydrogenase (G6PD) and its usefulness in the detection of a heterozygotic deficiency of G6PD].

Vives Corrons JL, Merino A, Pujades MA.

Sangre (Barc). 1986;31(4):467-75. Spanish. No abstract available.

PMID: 3787415 Similar articles Select item 647409236.

Hình 10

Mediterranean glucose 6-phosphate dehydrogenase (G6PD) deficiency--near normal decay of the mutant enzyme protein in circulating erythrocytes.

Morelli A, Benatti U, Guida L, De Flora A.

Scand J Haematol. 1984 Aug;33(2):144-54.

PMID: 6474092 Similar articles Select item 1297157237.

Semiquantitative screening test for G6PD deficiency detects severe deficiency but misses a substantial proportion of partially-deficient females.

Ainoon O, Alawiyah A, Yu YH, Cheong SK, Hamidah NH, Boo NY, Zaleha M.

Southeast Asian J Trop Med Public Health. 2003 Jun;34(2):405-14.

PMID: 12971572 Similar articles Select item 1083089938.

Hình 11

Transient inhibition of glucose utilization by erythrocytes during the acute stage of typhoid fever.

Khajehdehi P.

Microbiol Res. 2000 Apr;155(1):45-7.

PMID: 10830899 Similar articles Select item 1511730739.

Rapid epidemiologic assessment of glucose-6-phosphate dehydrogenase deficiency in malaria-endemic areas in Southeast Asia using a novel diagnostic kit.

Jalloh A, Tantular IS, Pusarawati S, Kawilarang AP, Kerong H, Lin K, Ferreira MU, Matsuoka H, Arai M, Kita K, Kawamoto F.

Trop Med Int Health. 2004 May;9(5):615-23.

PMID: 15117307 Free Article Similar articles Select item 643165640.

Depression of erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity in enteric fever.

Crowell SB, Crowell EB Jr, Mathew M.

Trans R Soc Trop Med Hyg. 1984;78(2):183-6.

PMID: 6431656Similar articles

G6PD Deficiency and Hemoglobinopathies: Molecular Epidemiological Characteristics and Healthy Effects o­n Malaria Endemic Bioko Island, Equatorial Guinea.

Lin M, Yang LY, Xie DD, Chen JT, Nguba SM, Ehapo CS, Zhan XF, Eyi JU, Matesa RA, Obono MM, Yang H, Yang HT, Cheng JD.

PLoS o­ne. 2015 Apr 27;10(4):e0123991. doi: 10.1371/journal.pone.0123991. eCollection 2015.

PMID: 25915902 Free PMC Article Similar articles Select item 1520249242.

Investigation of glucose 6-phosphate dehydrogenase (G6PD) kinetics for normal and G6PD-deficient persons and the effects of some drugs.

Ozmen I, Ciftçi M, Küfrevioğlu OI, Curük MA.

J Enzyme Inhib Med Chem. 2004 Feb;19(1):45-50.

PMID: 15202492 Similar articles Select item 1797808743.

Hình 12

Glucose-6-phosphate dehydrogenase deficiency and antimalarial drug development.

Beutler E, Duparc S; G6PD Deficiency Working Group.

Am J Trop Med Hyg. 2007 Oct;77(4):779-89. Review.

PMID: 17978087 Similar articles Select item 2109213744.

Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali.

Kone AK, Sagara I, Thera MA, Dicko A, Guindo A, Diakite S, Kurantsin-Mills J, Djimde A, Walcourt A, Doumbo O.

Malar J. 2010 Nov 21;9:332. doi: 10.1186/1475-2875-9-332.

PMID: 21092137 Free PMC Article Similar articles Select item 2068479245.

Population screening for glucose-6-phosphate dehydrogenase deficiencies in Isabel Province, Solomon Islands, using a modified enzyme assay o­n filter paper dried bloodspots.

Kuwahata M, Wijesinghe R, Ho MF, Pelecanos A, Bobogare A, Landry L, Bugora H, Vallely A, McCarthy J.

Malar J. 2010 Aug 5;9:223. doi: 10.1186/1475-2875-9-223.

PMID: 20684792 Free PMC Article Similar articles Select item 343805946.

Superoxide dismutase activity and reduced glutathione content in cataractous lens of patients with glucose-6-phosphate dehydrogenase deficiency.

Vanella A, Gorgone G, Cavallaro N, Castorina C, Campisi A, Di Giacomo C, Bousquet E, Li Volti S, Mollica F.

Ophthalmic Paediatr Genet. 1987 Nov;8(3):191-5.

PMID: 3438059 Similar articles Select item 1761100647.

Hình 13

G6PD deficiency: the genotype-phenotype association.

Mason PJ, Bautista JM, Gilsanz F.

Blood Rev. 2007 Sep;21(5):267-83. Epub 2007 Jul 3. Review. Erratum in: Blood Rev. 2010 Jan;24(1):49.

PMID: 17611006 Similar articles Select item 1817777748.

Glucose-6-phosphate dehydrogenase deficiency.

Cappellini MD, Fiorelli G.

Lancet. 2008 Jan 5;371(9606):64-74. doi: 10.1016/S0140-6736(08)60073-2. Review.

PMID: 18177777 Similar articles Select item 766771949.

The use of primaquine in malaria infected patients with red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency in Myanmar.

Myat-Phone-Kyaw, Myint-Oo, Aung-Naing, Aye-Lwin-Htwe.

Southeast Asian J Trop Med Public Health. 1994 Dec;25(4):710-3.

PMID: 7667719 Similar articles Select item 1550651950.

[Glucose 6-phosphate dehydrogenase deficiency: a protection against malaria and a risk for hemolytic accidents].

Wajcman H, Galactéros F.

C R Biol. 2004 Aug;327(8):711-20. Review. French.

PMID: 15506519 Similar articles Select item 1736598851.

Inherited, non-spherocytic haemolysis due to deficiency of glucose-6-phosphate dehydrogenase.

Ronquist G, Theodorsson E.

Scand J Clin Lab Invest. 2007;67(1):105-11. Review.

PMID: 17365988 Similar articles Select item 2745805252.

Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis.

Siler U, Romao S, Tejera E, Pastukhov O, Kuzmenko E, Valencia RG, Meda Spaccamela V, Belohradsky BH, Speer O, Schmugge M, Kohne E, Hoenig M, Freihorst J, Schulz AS, Reichenbach J.

J Allergy Clin Immunol. 2017 Jan;139(1):212-219.e3. doi: 10.1016/j.jaci.2016.04.041. Epub 2016 Jul 22.

PMID: 27458052 Similar articles Select item 2531201553.

Noninferiority of glucose-6-phosphate dehydrogenase deficiency diagnosis by a point-of-care rapid test vs the laboratory fluorescent spot test demonstrated by copper inhibition in normal human red blood cells.

Baird JK, Dewi M, Subekti D, Elyazar I, Satyagraha AW.

Transl Res. 2015 Jun;165(6):677-88. doi: 10.1016/j.trsl.2014.09.009. Epub 2014 Sep 28.

PMID: 25312015 Free PMC Article Similar articles Select item 2624983454.

Glucose-6-phosphate dehydrogenase deficiency among malaria patients of Honduras: a descriptive study of archival blood samples.

Zúñiga MÁ, Mejía RE, Sánchez AL, Sosa-Ochoa WH, Fontecha GA.

Malar J. 2015 Aug 7;14:308. doi: 10.1186/s12936-015-0823-z.

PMID: 26249834 Free PMC Article Similar articles Select item 2428997355.

Should blood donors be routinely screened for glucose-6-phosphate dehydrogenase deficiency? A systematic review of clinical studies focusing o­n patients transfused with glucose-6-phosphate dehydrogenase-deficient red cells.

Renzaho AM, Husser E, Polonsky M.

Transfus Med Rev. 2014 Jan;28(1):7-17. doi: 10.1016/j.tmrv.2013.10.003. Epub 2013 Oct 30. Review.

PMID: 24289973 Similar articles Select item 230745456.

A new glucose-6-phosphate dehydrogenase variant with congenital nonspherocytic hemolytic anemia (G6PD Genova). Biochemical characterization and mosaicism expression in the heterozygote.

Gaetani GF, Galiano S, Melani C, Miglino M, Forni GL, Napoli G, Perrone L, Ferraris AM.

Hum Genet. 1990 Mar;84(4):337-40.

PMID: 2307454 Similar articles Select item 730146457.

Glucose-6-phosphate dehydrogenase red blood cell phenotype in GdMediterranean heterozygous females and hemizygous males at birth.

Sanna G, Frau F, De Virgiliis S, Piu P, Bertolino F, Cao A.

Pediatr Res. 1981 Nov;15(11):1443-6.

PMID: 7301464 Similar articles Select item 1035786158.

Field trials of a rapid test for G6PD deficiency in combination with a rapid diagnosis of malaria.

Tantular IS, Iwai K, Lin K, Basuki S, Horie T, Htay HH, Matsuoka H, Marwoto H, Wongsrichanalai C, Dachlan YP, Kojima S, Ishii A, Kawamoto F.

Trop Med Int Health. 1999 Apr;4(4):245-50.

PMID: 10357861 Free Article Similar articles Select item 2633734459.

Hyperglycaemia per se does not affect erythrocyte glucose-6-phosphate dehydrogenase activity in ketosis-prone diabetes.

Choukem SP, Sobngwi E, Garnier JP, Letellier S, Mauvais-Jarvis F, Calvo F, Gautier JF.

Diabetes Metab. 2015 Sep;41(4):326-30. doi: 10.1016/j.diabet.2014.07.002. Epub 2015 Sep 1.

PMID: 26337344 Similar articles Select item 2710951560.

Prevalence and hematological indicators of G6PD deficiency in malaria-infected patients.

Kotepui M, Uthaisar K, PhunPhuech B, Phiwklam N.

Infect Dis Poverty. 2016 Apr 25;5:36. doi: 10.1186/s40249-016-0130-0.

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First evaluation of glucose-6-phosphate dehydrogenase (G6PD) deficiency in vivax malaria endemic regions in the Republic of Korea.

Goo YK, Ji SY, Shin HI, Moon JH, Cho SH, Lee WJ, Kim JY.

PLoS o­ne. 2014 May 22;9(5):e97390. doi: 10.1371/journal.pone.0097390. eCollection 2014.

PMID: 24853873 Free PMC Article Similar articles Select item 400476362.

Entrapment of normal and mutant glucose 6-phosphate dehydrogenase (G6PD) within G6PD deficient erythrocytes.

De Flora A, Morelli A, Benatti U.

Bibl Haematol. 1985;(51):50-6.

PMID: 4004763 Similar articles Select item 969443563.

Glucose-6-phosphate dehydrogenase deficiency and malaria.

Ruwende C, Hill A.

J Mol Med (Berl). 1998 Jul;76(8):581-8. Review.

PMID: 9694435 Similar articles Select item 2216427964.

Performance of the CareStart™ G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening.

Kim S, Nguon C, Guillard B, Duong S, Chy S, Sum S, Nhem S, Bouchier C, Tichit M, Christophel E, Taylor WR, Baird JK, Menard D.

PLoS o­ne. 2011;6(12):e28357. doi: 10.1371/journal.pone.0028357. Epub 2011 Dec 2.

PMID: 22164279 Free PMC Article Similar articles Select item 2704096065.

Glucose-6-Phosphate Dehydrogenase Deficiency.

Luzzatto L, Nannelli C, Notaro R.

Hematol o­ncol Clin North Am. 2016 Apr;30(2):373-93. doi: 10.1016/j.hoc.2015.11.006. Review.

PMID: 27040960 Similar articles Select item 351198966.

Pathways for the reduction of oxidized glutathione in the Plasmodium falciparum-infected erythrocyte: can parasite enzymes replace host red cell glucose-6-phosphate dehydrogenase?

Roth EF Jr, Schulman S, Vanderberg J, Olson J.

Blood. 1986 Mar;67(3):827-30.

PMID: 3511989 Free Article Similar articles Select item 2254600967.

Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.

Van Malderen C, Van Geertruyden JP, Machevo S, González R, Bassat Q, Talisuna A, Yeka A, Nabasumba C, Piola P, Daniel A, Turyakira E, Forret P, Van Overmeir C, van Loen H, Robert A, D' Alessandro U.

Malar J. 2012 Jul 10;11:139. doi: 10.1186/1475-2875-11-139.

PMID: 22546009 Free PMC Article Similar articles Select item 357628268.

Malaria and glucose-6-phosphate dehydrogenase deficiency in North Sumatra, Indonesia.

Matsuoka H, Ishii A, Panjaitan W, Sudiranto R.

Southeast Asian J Trop Med Public Health. 1986 Dec;17(4):530-6.

PMID: 3576282 Similar articles Select item 238651269.

Prognosis of hemolytic anemia in G6PD- subjects. Multifactorial cluster analysis of biochemical characteristics of red cell age groups.

Yermakov NV, Jacobasch G, Krekhnov BV, Ermakova TA.

Biomed Biochim Acta. 1990;49(2-3):S242-6.

PMID: 2386512 Similar articles Select item 1536971670.

G6PD/PK ratio: a reliable parameter to identify glucose-6-phosphate dehydrogenase deficiency associated with microcytic anemia in heterozygous subjects.

Tagarelli A, Piro A, Tagarelli G, Bastone L, Paleari R, Mosca A.

Clin Biochem. 2004 Oct;37(10):863-6.

PMID: 15369716 Similar articles Select item 1976942271.

Perioperative management of the glucose-6-phosphate dehydrogenase deficient patient: a review of literature.

Elyassi AR, Rowshan HH.

Anesth Prog. 2009 Autumn;56(3):86-91. doi: 10.2344/0003-3006-56.3.86. Review.

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Prevalence of G6PD deficiency in selected populations from two previously high malaria endemic areas of Sri Lanka.

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