Trong 10 năm trở lại đây, số bệnh nhân sốt rét và số ký sinh trùng sốt rét có xu hướng giảm dần và ít đi ở nhiều vùng sốt rét lưu hành trên toàn cầu và ngay cả Việt Nam. Tuy nhiên, số ca mang ký sinh trùng không biểu hiện triệu chứng (asymptomatic carriers) hay số ca có ký sinh trùng thấp dưới ngưỡng phát hiện của kính hiển vi và test chẩn đoán nhanh (submicroscopic/ undermicroscopy detection)còn tồn tại nhiều trong cộng đồng là một mối đe dọa hay là một rào cản về mặt kỹ thuật trong lộ trình tiến tới loại trừ sốt rét trên thế giới cũng như tại Việt Nam.

Gần đây, nhiều nghiên cứu phát triển các kỹ thuật sinh học phân tử hiện đại có độ nhạy, độ đặc hiệu cvaf độ chính xác cao đã giúp phát hiện một tỷ lệ rất lớn trong cộng đồng về người lành mang trùng như thế bằng các ky thuật LAMP, nested-PCR, RT-PCR hay ultra-PCR. Điều đó đặt ra câu hỏi làm thế nào để định nghĩa mà xác định một ngưỡng tỷ lệ dương tính trong cộng đồng để làm thế nào chúng ta có thể can thiệp bằng các chiến lược khác nhau, chẳng hạn điều trị chỉ định thuốc hàng loạt (mass drug administration_MDA) trong cộng đồng hay không thì đến nay vẫn còn chưa có khuyến cáo chính thức từ các cơ quan chức năng. Do vậy, nghiên cứu tiếp cận các khía cạnh như thế là rất cần thiết

Absence of Asymptomatic Malaria Infection in a Cross-sectional Study in Iranshahr District, Iran under Elimination Programmes.Pirahmadi S, Zakeri S, Raeisi A.Iran J Parasitol. 2017 Jan-Mar;12(1):90-100.PMID: 28761465 Free PMC Article Similar articlesSelect item 2985908964.

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Prevalence and risk factors for asymptomatic malaria and genotyping of glucose 6-phosphate (G6PD) deficiencies in a vivax-predominant setting, Lao PDR: implications for sub-national elimination goals.Lover AA, Dantzer E, Hongvanthong B, Chindavongsa K, Welty S, Reza T, Khim N, Menard D, Bennett A.Malar J. 2018 Jun 1;17(1):218. doi: 10.1186/s12936-018-2367-5.PMID: 29859089 Free PMC Article Similar articles Select item 2229728365.

Absence of Asymptomatic Malaria Infection in a Cross-sectional Study in Iranshahr District, Iran under Elimination Programmes.Pirahmadi S, Zakeri S, Raeisi A.Iran J Parasitol. 2017 Jan-Mar;12(1):90-100.PMID: 28761465 Free PMC Article Similar articlesSelect item 2985908964.

Prevalence and risk factors for asymptomatic malaria and genotyping of glucose 6-phosphate (G6PD) deficiencies in a vivax-predominant setting, Lao PDR: implications for sub-national elimination goals.Lover AA, Dantzer E, Hongvanthong B, Chindavongsa K, Welty S, Reza T, Khim N, Menard D, Bennett A.Malar J. 2018 Jun 1;17(1):218. doi: 10.1186/s12936-018-2367-5.PMID: 29859089 Free PMC Article Similar articles Select item 2229728365.

Molecular screening of Plasmodium infections among migrant workers in Thailand.Kritsiriwuthinan K, Ngrenngarmlert W.J Vector Borne Dis. 2011 Dec;48(4):214-8.PMID: 22297283 Free Article Similar articlesSelect item 2842039966.

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Distinct parasite populations infect individuals identified through passive and active case detection in a region of declining malaria transmission in southern Zambia.Searle KM, Katowa B, Kobayashi T, Siame MNS, Mharakurwa S, Carpi G, Norris DE, Stevenson JC, Thuma PE, Moss WJ; Southern Africa International Centers of Excellence for Malaria Research.Malar J. 2017 Apr 19;16(1):154. doi: 10.1186/s12936-017-1810-3.PMID: 28420399 Free PMC Article Similar articlesSelect item 2930425867.

The Relative Contribution of Symptomatic and Asymptomatic Plasmodium vivax and Plasmodium falciparum Infections to the Infectious Reservoir in a Low-Endemic Setting in Ethiopia.Tadesse FG, Slater HC, Chali W, Teelen K, Lanke K, Belachew M, Menberu T, Shumie G, Shitaye G, Okell LC, Graumans W, van Gemert GJ, Kedir S, Tesfaye A, Belachew F, Abebe W, Mamo H, Sauerwein R, Balcha T, Aseffa A, Yewhalaw D, Gadisa E, Drakeley C, Bousema T.Clin Infect Dis. 2018 Jun 1;66(12):1883-1891. doi: 10.1093/cid/cix1123.PMID: 29304258 Similar articlesSelect item 2902917968.

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Sustained Malaria Control Over an 8-Year Period in Papua New Guinea: The Challenge of Low-Density Asymptomatic Plasmodium Infections.Koepfli C, Ome-Kaius M, Jally S, Malau E, Maripal S, Ginny J, Timinao L, Kattenberg JH, Obadia T, White M, Rarau P, Senn N, Barry AE, Kazura JW, Mueller I, Robinson LJ.J Infect Dis. 2017 Dec 12;216(11):1434-1443. doi: 10.1093/infdis/jix507.PMID: 29029179 Free PMC Article Similar articlesSelect item 2532607969.

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Detection of mixed infection level of Plasmodium falciparum and Plasmodium vivax by SYBR Green I-based real-time PCR in North Gondar, north-west Ethiopia.Tajebe A, Magoma G, Aemero M, Kimani F.Malar J. 2014 Oct 18;13:411. doi: 10.1186/1475-2875-13-411.PMID: 25326079 Free PMC Article Similar articles Select item 2290939970.

Mass blood survey for malaria: pooling and real-time PCR combined with expert microscopy in north-west Thailand.Congpuong K, Saejeng A, Sug-Aram R, Aruncharus S, Darakapong A, Meshnick SR, Satimai W.Malar J. 2012 Aug 21;11:288. doi: 10.1186/1475-2875-11-288.PMID: 22909399 Free PMC Article Similar articles Select item 1238993771.

Comparison of field and expert laboratory microscopy for active surveillance for asymptomatic Plasmodium falciparum and Plasmodium vivax in western Thailand.Coleman RE, Maneechai N, Rachaphaew N, Kumpitak C, Miller RS, Soyseng V, Thimasarn K, Sattabongkot J.Am J Trop Med Hyg. 2002 Aug;67(2):141-4.PMID: 12389937 Similar articlesSelect item 2901633572.

Performance of Loop-Mediated Isothermal Amplification for the Identification of Submicroscopic Plasmodium falciparum Infection in Uganda.Katrak S, Murphy M, Nayebare P, Rek J, Smith M, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B.Am J Trop Med Hyg. 2017 Dec;97(6):1777-1781. doi: 10.4269/ajtmh.17-0225. Epub 2017 Oct 5.PMID: 29016335 Similar articles Select item 2756627473.

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Prevalence of malaria in pregnancy in southern Laos: a cross-sectional survey.Briand V, Le Hesran JY, Mayxay M, Newton PN, Bertin G, Houzé S, Keomany S, Inthavong Y, Vannavong N, Chindavongsa K, Hongvanthong B, Fievet N.Malar J. 2016 Aug 26;15(1):436. doi: 10.1186/s12936-016-1492-2.PMID: 27566274 Free PMC Article Similar articles Select item 2762817874.

Characterizing microscopic and submicroscopic malaria parasitaemia at three sites with varied transmission intensity in Uganda.Rek J, Katrak S, Obasi H, Nayebare P, Katureebe A, Kakande E, Arinaitwe E, Nankabirwa JI, Jagannathan P, Drakeley C, Staedke SG, Smith DL, Bousema T, Kamya M, Rosenthal PJ, Dorsey G, Greenhouse B.Malar J. 2016 Sep 15;15:470. doi: 10.1186/s12936-016-1519-8.PMID: 27628178 Free PMC Article Similar articles Select item 2177480575.

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Specific, sensitive and rapid detection of human plasmodium knowlesi infection by loop-mediated isothermal amplification (LAMP) in blood samples.Lau YL, Fong MY, Mahmud R, Chang PY, Palaeya V, Cheong FW, Chin LC, Anthony CN, Al-Mekhlafi AM, Chen Y.Malar J. 2011 Jul 20;10:197. doi: 10.1186/1475-2875-10-197.PMID: 21774805 Free PMC Article Similar articles Select item 2479548076.

Field evaluation of a real-time fluorescence loop-mediated isothermal amplification assay, RealAmp, for the diagnosis of malaria in Thailand and India.Patel JC, Lucchi NW, Srivastava P, Lin JT, Sug-Aram R, Aruncharus S, Bharti PK, Shukla MM, Congpuong K, Satimai W, Singh N, Udhayakumar V, Meshnick SR.J Infect Dis. 2014 Oct 15;210(8):1180-7. doi: 10.1093/infdis/jiu252. Epub 2014 May 1.PMID: 24795480 Similar articlesSelect item 2392759677.

Is a Plasmodium lactate dehydrogenase (pLDH) enzyme-linked immunosorbent (ELISA)-based assay a valid tool for detecting risky malaria blood donations in Africa?Atchade PS, Doderer-Lang C, Chabi N, Perrotey S, Abdelrahman T, Akpovi CD, Anani L, Bigot A, Sanni A, Candolfi E.Malar J. 2013 Aug 8;12:279. doi: 10.1186/1475-2875-12-279.PMID: 23927596 Free PMC Article Similar articles Select item 2687095878.

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Sensitive Detection of Plasmodium vivax Using a High-Throughput, Colourimetric Loop Mediated Isothermal Amplification (HtLAMP) Platform: A Potential Novel Tool for Malaria Elimination.Britton S, Cheng Q, Grigg MJ, Poole CB, Pasay C, William T, Fornace K, Anstey NM, Sutherland CJ, Drakeley C, McCarthy JS.PLoS Negl Trop Dis. 2016 Feb 12;10(2):e0004443. doi: 10.1371/journal.pntd.0004443. eCollection 2016 Feb.PMID: 26870958 Free PMC Article Similar articles Select item 3009646279.

Evaluation of malaria multiplex/nested PCR performance at low parasite densities and mixed infection in Iran: A country close to malaria elimination.Mirahmadi H, Shahrakipour A, Mehravaran A, Khorashad AS, Rahmati-Balaghaleh M, Zarean M.Infect Genet Evol. 2018 Aug 7;65:283-287. doi: 10.1016/j.meegid.2018.08.005. [Epub ahead of print]. PMID: 30096462 Similar articlesSelect item 2588881880.

Comparison of a PfHRP2-based rapid diagnostic test and PCR for malaria in a low prevalence setting in rural southern Zambia: implications for elimination.Laban NM, Kobayashi T, Hamapumbu H, Sullivan D, Mharakurwa S, Thuma PE, Shiff CJ, Moss WJ; Southern Africa International Centers of Excellence for Malaria Research.Malar J. 2015 Jan 28;14:25. doi: 10.1186/s12936-015-0544-3. PMID: 25888818 Free PMC Article Similar articles

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Direct detection of falciparum and non-falciparum malaria DNA from a drop of blood with high sensitivity by the dried-LAMP system.Hayashida K, Kajino K, Simukoko H, Simuunza M, Ndebe J, Chota A, Namangala B, Sugimoto C.Parasit Vectors. 2017 Jan 13;10(1):26. doi: 10.1186/s13071-016-1949-8. PMID: 28086864 Free PMC Article Similar articles Select item 2589036882.

Comparison of rapid diagnostic test Plasmotec Malaria-3, microscopy, and quantitative real-time PCR for diagnoses of Plasmodium falciparum and Plasmodium vivax infections in Mimika Regency, Papua, Indonesia.Fransisca L, Kusnanto JH, Satoto TB, Sebayang B, Supriyanto, Andriyan E, Bangs MJ.Malar J. 2015 Mar 5;14:103. doi: 10.1186/s12936-015-0615-5.PMID: 25890368 Free PMC Article Similar articles Select item 2830216883.

Comparison of the diagnostic performance of microscopic examination with nested polymerase chain reaction for optimum malaria diagnosis in Upper Myanmar.Kang JM, Cho PY, Moe M, Lee J, Jun H, Lee HW, Ahn SK, Kim TI, Pak JH, Myint MK, Lin K, Kim TS, Na BK.Malar J. 2017 Mar 16;16(1):119. doi: 10.1186/s12936-017-1765-4.PMID: 28302168 Free PMC Article Similar articles Select item 2251319284.

Comparison of molecular tests for the diagnosis of malaria in Honduras.Fontecha GA, Mendoza M, Banegas E, Poorak M, De Oliveira AM, Mancero T, Udhayakumar V, Lucchi NW, Mejia RE.Malar J. 2012 Apr 18;11:119. doi: 10.1186/1475-2875-11-119.PMID: 22513192 Free PMC Article Similar articles Select item 2370613285.

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Epidemiology of Plasmodium infections in Flores Island, Indonesia using real-time PCR.Kaisar MM, Supali T, Wiria AE, Hamid F, Wammes LJ, Sartono E, Luty AJ, Brienen EA, Yazdanbakhsh M, van Lieshout L, Verweij JJ.Malar J. 2013 May 24;12:169. doi: 10.1186/1475-2875-12-169.PMID: 23706132 Free PMC Article Similar articles Select item 2472122786.

Detection of Plasmodium vivax and Plasmodium falciparum DNA in human saliva and urine: loop-mediated isothermal amplification for malaria diagnosis.Ghayour Najafabadi Z, Oormazdi H, Akhlaghi L, Meamar AR, Nateghpour M, Farivar L, Razmjou E.Acta Trop. 2014 Aug;136:44-9. doi: 10.1016/j.actatropica.2014.03.029. Epub 2014 Apr 8.PMID: 24721227 Similar articles Select item 2420664987.

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An innovative tool for moving malaria PCR detection of parasite reservoir into the field.Canier L, Khim N, Kim S, Sluydts V, Heng S, Dourng D, Eam R, Chy S, Khean C, Loch K, Ken M, Lim H, Siv S, Tho S, Masse-Navette P, Gryseels C, Uk S, Van Roey K, Grietens KP, Sokny M, Thavrin B, Chuor CM, Deubel V, Durnez L, Coosemans M, Ménard D.Malar J. 2013 Nov 9;12:405. doi: 10.1186/1475-2875-12-405.PMID: 24206649 Free PMC Article Similar articlesSelect item 1756779488.

Detection of four Plasmodium species by genus- and species-specific loop-mediated isothermal amplification for clinical diagnosis.Han ET, Watanabe R, Sattabongkot J, Khuntirat B, Sirichaisinthop J, Iriko H, Jin L, Takeo S, Tsuboi T.J Clin Microbiol. 2007 Aug;45(8):2521-8. Epub 2007 Jun 13.PMID: 17567794 Free PMC Article Similar articles Select item 2651193289.

Performance of four HRP-2/pLDH combination rapid diagnostic tests and field microscopy as screening tests for malaria in pregnancy in Indonesia: a cross-sectional study.Ahmed R, Levy EI, Maratina SS, de Jong JJ, Asih PB, Rozi IE, Hawley W, Syafruddin D, ter Kuile F.Malar J. 2015 Oct 29;14:420. doi: 10.1186/s12936-015-0943-5.PMID: 26511932 Free PMC Article Similar articles Select item 2268206590.

Simultaneous detection of Plasmodium vivax and Plasmodium falciparum gametocytes in clinical isolates by multiplex-nested RT-PCR.Kuamsab N, Putaporntip C, Pattanawong U, Jongwutiwes S.Malar J. 2012 Jun 10;11:190. doi: 10.1186/1475-2875-11-190.PMID: 22682065 Free PMC Article Similar articles Select item 2599691691.

Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea.Koepfli C, Robinson LJ, Rarau P, Salib M, Sambale N, Wampfler R, Betuela I, Nuitragool W, Barry AE, Siba P, Felger I, Mueller I.PLoS o­ne. 2015 May 21;10(5):e0126747. doi: 10.1371/journal.pone.0126747. eCollection 2015.PMID: 25996916 Free PMC Article Similar articles Select item 2693148892.

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Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting.Hustedt J, Canavati SE, Rang C, Ashton RA, Khim N, Berne L, Kim S, Sovannaroth S, Ly P, Ménard D, Cox J, Meek S, Roca-Feltrer A.Malar J. 2016 Mar 1;15:132. doi: 10.1186/s12936-016-1191-z. PMID: 26931488 Free PMC Article Similar articles Select item 2363340593.

Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda.Hopkins H, González IJ, Polley SD, Angutoko P, Ategeka J, Asiimwe C, Agaba B, Kyabayinze DJ, Sutherland CJ, Perkins MD, Bell D.J Infect Dis. 2013 Aug 15;208(4):645-52. doi: 10.1093/infdis/jit184. Epub 2013 Apr 30. Erratum in: J Infect Dis. 2014 May 1;209(9):1494. PMID: 23633405 Free PMC Article Similar articles Select item 2562703794.

Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar.Cook J, Aydin-Schmidt B, González IJ, Bell D, Edlund E, Nassor MH, Msellem M, Ali A, Abass AK, Mårtensson A, Björkman A.Malar J. 2015 Jan 28;14:43. doi: 10.1186/s12936-015-0573-y.PMID: 25627037 Free PMC Article Similar articlesSelect item 2877821095.

Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study.Rosas-Aguirre A, Guzman-Guzman M, Gamboa D, Chuquiyauri R, Ramirez R, Manrique P, Carrasco-Escobar G, Puemape C, Llanos-Cuentas A, Vinetz JM.Malar J. 2017 Aug 4;16(1):312. doi: 10.1186/s12936-017-1957-y.PMID: 28778210 Free PMC Article Similar articles Select item 2782486696.

A Field-Tailored Reverse Transcription Loop-Mediated Isothermal Assay for High Sensitivity Detection of Plasmodium falciparum Infections.Kemleu S, Guelig D, Eboumbou Moukoko C, Essangui E, Diesburg S, Mouliom A, Melingui B, Manga J, Donkeu C, Epote A, Texier G, LaBarre P, Burton R, Ayong L.PLoS o­ne. 2016 Nov 8;11(11):e0165506. doi: 10.1371/journal.pone.0165506. eCollection 2016.PMID: 27824866 Free PMC Article Similar articles Select item 2991449097.

In situ loop-mediated isothermal amplification (LAMP) for identification of Plasmodium species in wide-range thin blood smears.Hashimoto M, Sakamoto H, Ido Y, Tanaka M, Yatsushiro S, Kajimoto K, Kataoka M.Malar J. 2018 Jun 19;17(1):235. doi: 10.1186/s12936-018-2381-7.PMID: 29914490 Free PMC Article Similar articles Select item 2353714598.

Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training o­n the proficiency of laboratory technicians in species identification.Obare P, Ogutu B, Adams M, Odera JS, Lilley K, Dosoo D, Adhiambo C, Owusu-Agyei S, Binka F, Wanja E, Johnson J.Malar J. 2013 Mar 27;12:113. doi: 10.1186/1475-2875-12-113.PMID: 23537145 Free PMC Article Similar articles Select item 2092592899.

Comparison of real-time PCR and microscopy for malaria parasite detection in Malawian pregnant women.Rantala AM, Taylor SM, Trottman PA, Luntamo M, Mbewe B, Maleta K, Kulmala T, Ashorn P, Meshnick SR.Malar J. 2010 Oct 6;9:269. doi: 10.1186/1475-2875-9-269.PMID: 20925928 Free PMC Article Similar articles Select item 29251261100.

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Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening patients with imported malaria in a non-endemic setting.Ponce C, Kaczorowski F, Perpoint T, Miailhes P, Sigal A, Javouhey E, Gillet Y, Jacquin L, Douplat M, Tazarourte K, Potinet V, Simon B, Lavoignat A, Bonnot G, Sow F, Bienvenu AL, Picot S.Parasite. 2017;24:53. doi: 10.1051/parasite/2017054. Epub 2017 Dec 18.PMID: 29251261 Free PMC Article Similar articles

SYBR Green real-time PCR-RFLP assay targeting the plasmodium cytochrome B gene a highly sensitive molecular tool for malaria parasite detection and species determination.Xu W, Morris U, Aydin-Schmidt B, Msellem MI, Shakely D, Petzold M, Björkman A, Mårtensson A.PLoS o­ne. 2015 Mar 16;10(3):e0120210. doi: 10.1371/journal.pone.0120210. eCollection 2015.PMID: 25774805 Free PMC Article Similar articles

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Molecular screening of Plasmodium infections among migrant workers in Thailand.Kritsiriwuthinan K, Ngrenngarmlert W.J Vector Borne Dis. 2011 Dec;48(4):214-8.PMID: 22297283 Free Article Similar articlesSelect item 2842039966.

Distinct parasite populations infect individuals identified through passive and active case detection in a region of declining malaria transmission in southern Zambia.Searle KM, Katowa B, Kobayashi T, Siame MNS, Mharakurwa S, Carpi G, Norris DE, Stevenson JC, Thuma PE, Moss WJ; Southern Africa International Centers of Excellence for Malaria Research.Malar J. 2017 Apr 19;16(1):154. doi: 10.1186/s12936-017-1810-3.PMID: 28420399 Free PMC Article Similar articlesSelect item 2930425867.

The Relative Contribution of Symptomatic and Asymptomatic Plasmodium vivax and Plasmodium falciparum Infections to the Infectious Reservoir in a Low-Endemic Setting in Ethiopia.Tadesse FG, Slater HC, Chali W, Teelen K, Lanke K, Belachew M, Menberu T, Shumie G, Shitaye G, Okell LC, Graumans W, van Gemert GJ, Kedir S, Tesfaye A, Belachew F, Abebe W, Mamo H, Sauerwein R, Balcha T, Aseffa A, Yewhalaw D, Gadisa E, Drakeley C, Bousema T.Clin Infect Dis. 2018 Jun 1;66(12):1883-1891. doi: 10.1093/cid/cix1123.PMID: 29304258 Similar articlesSelect item 2902917968.

Sustained Malaria Control Over an 8-Year Period in Papua New Guinea: The Challenge of Low-Density Asymptomatic Plasmodium Infections.Koepfli C, Ome-Kaius M, Jally S, Malau E, Maripal S, Ginny J, Timinao L, Kattenberg JH, Obadia T, White M, Rarau P, Senn N, Barry AE, Kazura JW, Mueller I, Robinson LJ.J Infect Dis. 2017 Dec 12;216(11):1434-1443. doi: 10.1093/infdis/jix507.PMID: 29029179 Free PMC Article Similar articlesSelect item 2532607969.

Detection of mixed infection level of Plasmodium falciparum and Plasmodium vivax by SYBR Green I-based real-time PCR in North Gondar, north-west Ethiopia.Tajebe A, Magoma G, Aemero M, Kimani F.Malar J. 2014 Oct 18;13:411. doi: 10.1186/1475-2875-13-411.PMID: 25326079 Free PMC Article Similar articles Select item 2290939970.

Mass blood survey for malaria: pooling and real-time PCR combined with expert microscopy in north-west Thailand.Congpuong K, Saejeng A, Sug-Aram R, Aruncharus S, Darakapong A, Meshnick SR, Satimai W.Malar J. 2012 Aug 21;11:288. doi: 10.1186/1475-2875-11-288.PMID: 22909399 Free PMC Article Similar articles Select item 1238993771.

Detection of four Plasmodium species by genus- and species-specific loop-mediated isothermal amplification for clinical diagnosis.Han ET, Watanabe R, Sattabongkot J, Khuntirat B, Sirichaisinthop J, Iriko H, Jin L, Takeo S, Tsuboi T.J Clin Microbiol. 2007 Aug;45(8):2521-8. Epub 2007 Jun 13.PMID: 17567794 Free PMC Article Similar articles Select item 2651193289.

Performance of four HRP-2/pLDH combination rapid diagnostic tests and field microscopy as screening tests for malaria in pregnancy in Indonesia: a cross-sectional study.Ahmed R, Levy EI, Maratina SS, de Jong JJ, Asih PB, Rozi IE, Hawley W, Syafruddin D, ter Kuile F.Malar J. 2015 Oct 29;14:420. doi: 10.1186/s12936-015-0943-5.PMID: 26511932 Free PMC Article Similar articles Select item 2268206590.

Simultaneous detection of Plasmodium vivax and Plasmodium falciparum gametocytes in clinical isolates by multiplex-nested RT-PCR.Kuamsab N, Putaporntip C, Pattanawong U, Jongwutiwes S.Malar J. 2012 Jun 10;11:190. doi: 10.1186/1475-2875-11-190.PMID: 22682065 Free PMC Article Similar articles Select item 2599691691.

Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea.Koepfli C, Robinson LJ, Rarau P, Salib M, Sambale N, Wampfler R, Betuela I, Nuitragool W, Barry AE, Siba P, Felger I, Mueller I.PLoS o­ne. 2015 May 21;10(5):e0126747. doi: 10.1371/journal.pone.0126747. eCollection 2015.PMID: 25996916 Free PMC Article Similar articles Select item 2693148892.

Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting.Hustedt J, Canavati SE, Rang C, Ashton RA, Khim N, Berne L, Kim S, Sovannaroth S, Ly P, Ménard D, Cox J, Meek S, Roca-Feltrer A.Malar J. 2016 Mar 1;15:132. doi: 10.1186/s12936-016-1191-z.PMID: 26931488 Free PMC Article Similar articles Select item 2363340593.

Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda.Hopkins H, González IJ, Polley SD, Angutoko P, Ategeka J, Asiimwe C, Agaba B, Kyabayinze DJ, Sutherland CJ, Perkins MD, Bell D.J Infect Dis. 2013 Aug 15;208(4):645-52. doi: 10.1093/infdis/jit184. Epub 2013 Apr 30. Erratum in: J Infect Dis. 2014 May 1;209(9):1494. PMID: 23633405 Free PMC Article Similar articles Select item 2562703794.

Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar.Cook J, Aydin-Schmidt B, González IJ, Bell D, Edlund E, Nassor MH, Msellem M, Ali A, Abass AK, Mårtensson A, Björkman A.Malar J. 2015 Jan 28;14:43. doi: 10.1186/s12936-015-0573-y.PMID: 25627037 Free PMC Article Similar articlesSelect item 2877821095.

Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study.Rosas-Aguirre A, Guzman-Guzman M, Gamboa D, Chuquiyauri R, Ramirez R, Manrique P, Carrasco-Escobar G, Puemape C, Llanos-Cuentas A, Vinetz JM.Malar J. 2017 Aug 4;16(1):312. doi: 10.1186/s12936-017-1957-y.PMID: 28778210 Free PMC Article Similar articles Select item 2782486696.

A Field-Tailored Reverse Transcription Loop-Mediated Isothermal Assay for High Sensitivity Detection of Plasmodium falciparum Infections.Kemleu S, Guelig D, Eboumbou Moukoko C, Essangui E, Diesburg S, Mouliom A, Melingui B, Manga J, Donkeu C, Epote A, Texier G, LaBarre P, Burton R, Ayong L.PLoS o­ne. 2016 Nov 8;11(11):e0165506. doi: 10.1371/journal.pone.0165506. eCollection 2016.PMID: 27824866 Free PMC Article Similar articles Select item 2991449097.

In situ loop-mediated isothermal amplification (LAMP) for identification of Plasmodium species in wide-range thin blood smears.Hashimoto M, Sakamoto H, Ido Y, Tanaka M, Yatsushiro S, Kajimoto K, Kataoka M.Malar J. 2018 Jun 19;17(1):235. doi: 10.1186/s12936-018-2381-7.PMID: 29914490 Free PMC Article Similar articles Select item 2353714598.

Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training o­n the proficiency of laboratory technicians in species identification.Obare P, Ogutu B, Adams M, Odera JS, Lilley K, Dosoo D, Adhiambo C, Owusu-Agyei S, Binka F, Wanja E, Johnson J.Malar J. 2013 Mar 27;12:113. doi: 10.1186/1475-2875-12-113.PMID: 23537145 Free PMC Article Similar articles Select item 2092592899.

Comparison of real-time PCR and microscopy for malaria parasite detection in Malawian pregnant women.Rantala AM, Taylor SM, Trottman PA, Luntamo M, Mbewe B, Maleta K, Kulmala T, Ashorn P, Meshnick SR.Malar J. 2010 Oct 6;9:269. doi: 10.1186/1475-2875-9-269.PMID: 20925928 Free PMC Article Similar articles Select item 29251261100.

Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening patients with imported malaria in a non-endemic setting.Ponce C, Kaczorowski F, Perpoint T, Miailhes P, Sigal A, Javouhey E, Gillet Y, Jacquin L, Douplat M, Tazarourte K, Potinet V, Simon B, Lavoignat A, Bonnot G, Sow F, Bienvenu AL, Picot S.Parasite. 2017;24:53. doi: 10.1051/parasite/2017054. Epub 2017 Dec 18.PMID: 29251261 Free PMC Article Similar articles

SYBR Green real-time PCR-RFLP assay targeting the plasmodium cytochrome B gene a highly sensitive molecular tool for malaria parasite detection and species determination.Xu W, Morris U, Aydin-Schmidt B, Msellem MI, Shakely D, Petzold M, Björkman A, Mårtensson A.PLoS o­ne. 2015 Mar 16;10(3):e0120210. doi: 10.1371/journal.pone.0120210. eCollection 2015.PMID: 25774805 Free PMC Article Similar articles

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