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Updated publications on malaria research in the world (2016-2017) (Part II)
Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes The clinical utility of primaquine (PQ), used as a racemic mixture of two enantiomers, is limited due to metabolism-linked hemolytic toxicity in individuals with genetic deficiency in glucose-6-phosphate dehyd...Pius S. Fasinu, Bharathi Avula, Babu L. Tekwani, N. P. Dhammika Nanayakkara, Yan-Hong Wang, H. M. T. Bandara Herath, James D. McChesney, Gregory A. Reichard, Sean R. Marcsisin, Mahmoud A. Elsohly, Shabana I. Khan, Ikhlas A. Khan and Larry A. Walker. Malaria Journal 2016 15:224 Most outdoor malaria transmission by behaviourally-resistantAnopheles arabiensisis mediated by mosquitoes that have previously been inside houses Anopheles arabiensis is stereotypical of diverse vectors that mediate residual malaria transmission globally, because it can feed outdoors upon humans or cattle, or enter but then rapi... Gerry F. Killeen, Nicodem J. Govella, Dickson W. Lwetoijera and Fredros O. Okumu Malaria Journal 2016 15:225 Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali Malaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age liv... Mahamoudou Touré, Daouda Sanogo, Soumaila Dembele, Sory Ibrahima Diawara, Karen Oppfeldt, Karin L. Schiøler, Dade Ben Haidara, Sékou F. Traoré, Michael Alifrangis, Flemming Konradsen and Seydou Doumbia Malaria Journal 2016 15:219 Effectiveness of the delivery of interventions to prevent malaria in pregnancy in Kenya Coverage with malaria in pregnancy interventions remains unacceptably low. Implementation research is needed to identify and quantify the bottlenecks for the delivery and use of these life-saving interventions... Stephanie Dellicour, Jenny Hill, Jane Bruce, Peter Ouma, Doris Marwanga, Peter Otieno, Meghna Desai, Mary J. Hamel, Simon Kariuki and Jayne Webster Malaria Journal 2016 15:221 The effects of electricity network development besides routine malaria control measures in an underdeveloped region in the pre-elimination phase The main purpose of this study was to investigate the effects of electricity network development on malaria transmission. The study was performed in the rural areas of three districts in Sistan-va-Baluchestan ...Shahrokh Izadi Malaria Journal 2016 15:222 Sexual reproduction in the mosquito is essential for the transmission of malaria parasites and a major target for transmission-blocking interventions. Male gametes need to locate and fertilize females in the c... Lucy M. Carter, Laura C. Pollitt, Laurence G. Wilson and Sarah E. ReeceMalaria Journal201615:220 Rosetting is associated with severe malaria and a primary cause of death inPlasmodium falciparuminfections. Detailed understanding of this adhesive phenomenon may enable the development of new therapies interfe... Patrick Wolfgang Kudella, Kirsten Moll, Mats Wahlgren, Achim Wixforth and Christoph WesterhausenMalaria Journal201615:223 The Indonesian archipelago is endemic for malaria. AlthoughPlasmodium falciparumandP. vivaxare the most common causes for malaria cases,P. malariaeandP. ovaleare also present in certain regions. Zoonotic... Wuryantari Setiadi, Herawati Sudoyo, Hidayat Trimarsanto, Boy Adventus Sihite, Riahdo Juliarman Saragih, Rita Juliawaty, Suradi Wangsamuda, Puji Budi Setia Asih and Din SyafruddinMalaria Journal201615:218 Controlling and preventive measures considerably reduced malaria incidence in Iran over the past few years, which confined the endemic areas to some regions in the southeastern Iran. The National Malaria Elimi... Khodadad Sheikhzadeh, Ali Akbar Haghdoost, Abbas Bahrampour, Farzaneh Zolala and Ahmad RaeisiMalaria Journal201615:209 Malaria in pregnancy is a major public health problem in Uganda; and it is the leading cause of anaemia among pregnant women and low birth weight in infants. Previous studies have noted poor quality of care in... Anthony K. Mbonye, Esther Buregyeya, Elizeus Rutebemberwa, Siân E. Clarke, Sham Lal, Kristian S. Hansen, Pascal Magnussen and Philip LaRussaMalaria Journal201615:212 Intravenous artesunate has replaced quinine as the first-line therapy for severe imported malaria, given its anti-malarial superiority shown in clinical trials conducted in endemic countries. Evidence for red ... Antonia Calvo-Cano, Joan Gómez-Junyent, Miguel Lozano, Pedro Castro, Joan Cid, Jose María Nicolás, Llorenç Quintó, Maite Martin, Jose Muñoz and Joaquim GasconMalaria Journal201615:216 Malaria in pregnancy contributes greatly to maternal morbidity and mortality in Uganda. Thus it is urgent to identify possible barriers that limit access to existing interventions. The aim of this study was to... Anthony K. Mbonye, Said M. Mohamud and James BagonzaMalaria Journal201615:211 Substandard and falsified anti-malarial medicines pose a serious threat to public health, especially in low-income countries. Appropriate technologies for drug quality analysis in resource-limited settings are... Felix Khuluza, Stephen Kigera, Richard W. O. Jähnke and Lutz HeideMalaria Journal201615:215 Integrated vector management (IVM) is the recommended approach for controlling some vector-borne diseases (VBD). In the face of current challenges to disease vector control, IVM is vital to achieve national ta... Michael Okia, Peter Okui, Myers Lugemwa, John M. Govere, Vincent Katamba, John B. Rwakimari, Betty Mpeka and Emmanuel ChandaMalaria Jour.2016 Asymptomatic falciparum malaria is associated with poorer cognitive performance in African schoolchildren and intermittent preventive treatment of malaria improves cognitive outcomes. However, the developmenta... Michael J. Boivin, Alla Sikorskii, Itziar Familiar-Lopez, Horacio Ruiseñor-Escudero, Mary Muhindo, James Kapisi, Victor Bigira, Judy K. Bass, Robert O. Opoka, Noeline Nakasujja, Moses Kamya and Grant DorseyMalaria Journal2016 Challenges persist in ensuring access to and optimal use of long-lasting, insecticidal bed nets (LLINs). Factors associated with ownership and use may differ depending on the history of malaria and prevention ...Kacey C. Ernst, Mary H. Hayden, Heather Olsen, Jamie L. Cavanaugh, Irene Ruberto, Maurice Agawo and Stephen MungaMalaria Journal201615:217 The identification of epidemiological pattern of infection withPlasmodium falciparumandPlasmodium vivaxin malaria-endemic area, where multiple episodes are common, is important for intervention programmes. Dinberu Seyoum, Yehenew Getachew Kifle, Virginie Rondeau, Delenasaw Yewhalaw, Luc Duchateau, Angel Rosas-Aguirre and Niko SpeybroeckMalaria Journal201615:208 Targeted malaria control interventions are expected to be cost-effective. Clinical, parasitological and serological markers of malaria transmission have been used to detect malaria transmission hotspots, but f... David Tiga Kangoye, Abdisalan Noor, Janet Midega, Joyce Mwongeli, Dora Mkabili, Polycarp Mogeni, Christine Kerubo, Pauline Akoo, Joseph Mwangangi, Chris Drakeley, Kevin Marsh, Philip Bejon and Patricia NjugunaMalaria Jour.2016 Plasmodiumcircumsporozoite protein (CSP) is a major surface antigen present in the sporozoite (Spz) stage of a malaria parasite. RTS, S vaccine, the most clinically advanced malaria v... Min Zhang, Izumi Kaneko, Tiffany Tsao, Robert Mitchell, Elizabeth H. Nardin, Shiroh Iwanaga, Masao Yuda and Moriya TsujiMalaria Journal201615:201 In eukaryotic genomes, deletion or amplification rates have been estimated to be a thousand more frequent than single nucleotide variation. InPlasmodium falciparum,relatively few transcription factors have been... Johann Beghain, Anne-Claire Langlois, Eric Legrand, Laura Grange, Nimol Khim, Benoit Witkowski, Valentine Duru, Laurence Ma, Christiane Bouchier, Didier Ménard, Richard E. Paul and Frédéric ArieyMalaria Journal201615:206 Despite high levels of naturally-acquired immunity (NAI) within local communities in malaria high transmission settings in Africa, such people often experience clinical disease during peak transmission months ... Leo BraackMalaria Journal201615:207 Cerebral malaria (CM) is a life-threatening disease, caused mainly byPlasmodium falciparumin humans. In adults only 1?2 % ofP. falciparum-infected hosts transit to the cerebral form of the disease while most ...Soumita Ghosh, Arjun Sengupta, Shobhona Sharma and Haripalsingh M. SonawatMalaria Journal201615:198 Escalating drug resistance in malaria parasites and lack of vaccine entails the discovery of novel drug targets and inhibitor molecules. The multi-component protein translation machinery is a rich source of su... Sameena KhanMalaria Journal201615:203 As malaria prevalence declines in many parts of the world due to widescale control efforts and as drug-resistant parasites begin to emerge, a quantitative understanding of human movement is becoming increasing... John M. Marshall, Mahamoudou Touré, André Lin Ouédraogo, Micky Ndhlovu, Samson S. Kiware, Ashley Rezai, Emmy Nkhama, Jamie T. Griffin, T. Deirdre Hollingsworth, Seydou Doumbia, Nicodem J. Govella, Neil M. Ferguson and Azra C. GhaniMalaria Journal201615:200 Anopheles nuneztovarisensu lato comprises cryptic species in northern South America, and the Brazilian populations encompass distinct genetic lineages within the Brazilian Amazon regi...Vera Margarete Scarpassa, Antonio Saulo Cunha-Machado and José Ferreira SaraivaMalaria Journal201615:205 Fine-scale targeting of interventions is increasingly important where epidemiological disease profiles depict high geographical stratifications. This study verified correlations between household biomass and m... Emmanuel W. Kaindoa, Gustav Mkandawile, Godfrey Ligamba, Louise A. Kelly-Hope and Fredros O. OkumuMalaria Journal201615:199 Malaria epidemiology in Mauritania has been characterized on the basis of epidemiological strata, defined by climatic and geographic features, which divide the country into three zones: Sahelian zone, Sahelo-S... Mohamed Ouldabdallahi Moukah, Ousmane Ba, Hampaté Ba, Mohamed Lemine Ould Khairy, Ousmane Faye, Hervé Bogreau, Frédéric Simard and Leonardo K. BascoMalaria Journal201615:204 Plasmodium vivax48/45 protein is expressed on the surface of gametocytes/gametes and plays a key role in gamete fusion during fertilization. This protein was recently expressed inEsc...Andres F. Vallejo, Nora L. Martinez, Alejandra Tobon, Jackeline Alger, Marcus V. Lacerda, Andrey V. Kajava, Myriam Arévalo-Herrera and Sócrates HerreraMalaria Jour2016 Despite declining prevalence of malaria in The Gambia, non-adherence to anti-malarial treatment still remains a challenge to control efforts. There is limited evidence on the socio-cultural factors that influe... Fatou Jaiteh, Susan Dierickx, Charlotte Gryseels, Sarah O?Neill, Umberto D?Alessandro, Susana Scott, Julie Balen and Koen Peeters GrietensMalaria Jour2016 In 2012, Uganda initiated nationwide deployment of malaria rapid diagnostic tests (RDT) as recommended by national guidelines. Yet growing concerns about RDT non-compliance in various settings have spurred cal...Emily White Johansson, Freddy Eric Kitutu, Chrispus Mayora, Phyllis Awor, Stefan Swartling Peterson, Henry Wamani and Helena HildenwallMalaria Journal201615:197 Malaria remains a major threat to some 3.2 billion persons globally. Malaria contributes heavily to the overall disease burden in Mozambique and is considered endemic. A cornerstone of Mozambique?s vector cont... Troy D. Moon, Caleb B. Hayes, Meridith Blevins, Melanie L. Lopez, Ann F. Green, Lazaro González-Calvo and Omo OluponaMalaria Journal201615:196 Yemen remains the country with the highest malaria transmission within the Arabian Peninsula and a source of imported cases to neighbouring countries. Jackie Cook, Lynn Grignard, Samira Al-Eryani, Mustafa Al-Selwei, Abraham Mnzava, Hafed Al-Yarie, Alison Rand, Immo Kleinschmidt and Chris DrakeleyMalaria Journal201615:193 Malaria remains a pervasive public health problem in sub-Saharan West Africa. Here mosquito vector populations were explored across four sites in Mali and the Republic of Guinea (Guinea Conakry). The study sam... Boubacar Coulibaly, Raymond Kone, Mamadou S. Barry, Becky Emerson, Mamadou B. Coulibaly, Oumou Niare, Abdoul H. Beavogui, Sekou F. Traore, Kenneth D. Vernick and Michelle M. RiehleMalaria Journal201615:191 Members of theAnopheles punctulatusgroup dominate Papua, Indonesia and Papua New Guinea (PNG), with a geographic range that extends south through Vanuatu.An. farautiandAn. punctulatusare the presumed major ... Brandy St. Laurent, Sukowati Supratman, Puji Budi Setia Asih, David Bretz, John Mueller, Helen Catherine Miller, Amirullah Baharuddin, Shinta, Asik Surya, Michelle Ngai, Ferdinand Laihad, Din Syafruddin, William A. Hawley, Frank H. Collins and Neil F. LoboMalaria Journal201615:192 For over a decade, Cambodia has implemented a number of policies and innovative strategies to increase access to quality malaria case management services and address the drivers of multi-drug resistance. This ... Joe Novotny, Amandeep Singh, Lek Dysoley, Siv Sovannaroth and Huy RekolMalaria Journal201615:194 Since 2012, rapid diagnostic tests (RDT) for malaria have been in use nationwide in Burkina Faso. The objective is to strengthen health professionals? diagnostic capabilities and promote good therapeutic pract...Sylvie Zongo, Valérie Farquet and Valéry RiddeMalaria Journal201615:190 Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders? perspectives are thus critical for informed recommendation of the vaccine in Tanz... Sally Mtenga, Angela Kimweri, Idda Romore, Ali Ali, Amon Exavery, Elisa Sicuri, Marcel Tanner, Salim Abdulla, John Lusingu and Shubi KafurukiMalaria Journal201615:189 Richard T. Sullivan, Isaac Ssewanyana, Samuel Wamala, Felistas Nankya, Prasanna Jagannathan, Jordan W. Tappero, Harriet Mayanja-Kizza, Mary K. Muhindo, Emmanuel Arinaitwe, Moses Kamya, Grant Dorsey, Margaret E. Feeney, Eleanor M. Riley, Chris J. Drakeley and Bryan GreenhouseMalaria Journal201615:188 Published on: 31 March 2016 Recent work has perfected yeast-based methods for measuring drug transport by thePlasmodium falciparumchloroquine (CQ) resistance transporter (PfCRT). Paul S. Callaghan, Amila Siriwardana, Matthew R. Hassett and Paul D. RoepeMalaria Journal201615:186 Cerebral malaria (CM) and severe malarial anaemia (SMA) are associated with neuro-developmental impairment in African children, but long-term mental health disorders in these children are not well defined. Richard Idro, Angelina Kakooza-Mwesige, Benjamin Asea, Keron Ssebyala, Paul Bangirana, Robert O. Opoka, Samson K. Lubowa, Margaret Semrud-Clikeman, Chandy C. John and Joyce NalugyaMalaria Journal201615:184 Artemisinin resistance inPlasmodium falciparumextends across Southeast Asia where it is associated with worsening partner drug resistance and a decline in the efficacy of frontline artemisinin-based combination... Kyaw Myo Tun, Atthanee Jeeyapant, Mallika Imwong, Min Thein, Sai Soe Moe Aung, Tin Maung Hlaing, Prayoon Yuentrakul, Cholrawee Promnarate, Mehul Dhorda, Charles J. Woodrow, Arjen M. Dondorp, Elizabeth A. Ashley, Frank M. Smithuis, Nicholas J. White and Nicholas P. J. DayMalaria Journal201615:185 Malaria remains a major cause of morbidity and mortality in children under 5 years of age in Equatorial Guinea. Early appropriate treatment can reduce progression of the illness to severe stages, thus reducing... Maria Romay-Barja, Jorge Cano, Policarpo Ncogo, Gloria Nseng, Maria A. Santana-Morales, Basilio Valladares, Matilde Riloha and Agustin BenitoMalaria Journal201615:187 Marcel HommelMalaria Journal201615:183 Population genomic features such as nucleotide diversity and linkage disequilibrium are expected to be strongly shaped by changes in population size, and might therefore be useful for monitoring the success of... Samantha M. O?Loughlin, Stephen M. Magesa, Charles Mbogo, Franklin Mosha, Janet Midega and Austin BurtMalaria Journal201615:182 SubclinicalPlasmodiumparasitaemia is an important reservoir for the transmission and persistence of malaria, particularly in low transmission areas. Rupam Tripura, Thomas J. Peto, Jeremy Chalk, Sue J. Lee, Pasathorn Sirithiranont, Chea Nguon, Mehul Dhorda, Lorenz von Seidlein, Richard J. Maude, Nicholas P. J. Day, Mallika Imwong, Nicholas J. White and Arjen M. DondorpMalaria Journal201615:181 The growing threat of insecticide resistance in mosquitoes and drug resistance in thePlasmodiumparasites increases the importance of ensuring appropriate malaria case management and enabling positive health-see... Amruta Dixit, Ming-Chieh Lee, Brittany Goettsch, Yaw Afrane, Andrew K. Githeko and Guiyun YanMalaria Journal201615:179 Bhutan has reduced its malaria incidence significantly in the last 5 years, and is aiming for malaria elimination by 2016. To assist with the management of the Bhutanese malaria elimination programme a spatial... Kinley Wangdi, Cathy Banwell, Michelle L. Gatton, Gerard C. Kelly, Rinzin Namgay and Archie CA ClementsMalaria Journal201615:180 Parasites play pivotal roles in host population dynamics and can have strong ecological impacts on hosts. Knowledge of the effects of parasites on hosts is often limited by the general observation of a fractio...María Calero-Riestra and Jesus T. GarcíaMalaria Journal201615:178 The World Health Organization recommends that persons of all ages suspected of malaria should receive a parasitological confirmation of malaria by use of malaria rapid diagnostic test (RDT) at community level,... Themba B. Phiri, Blessings N. Kaunda-Khangamwa, Andrew Bauleni, Tiyese Chimuna, David Melody, Humphreys Kalengamaliro, John H. Sande, Humphreys Kampira Nsona and Don P. MathangaMalaria Journal201615:177 Over the past 15 years, mortality and morbidity due to malaria have been reduced substantially in sub-Saharan Africa and local elimination has been achieved in some settings. This study addresses the bio-ecolo... Bernard L. Kouassi, Dziedzom K. de Souza, Andre Goepogui, Siradiou M. Balde, Lamia Diakité, Arsène Sagno, Georgina I. Djameh, Frédérique Chammartin, Penelope Vounatsou, Moses J. Bockarie, Jürg Utzinger and Benjamin G. KoudouMalaria Journal201615:175 Long-lasting insecticidal nets (LLINs) are the first line choice for malaria vector control in sub-Saharan Africa, with most countries adopting universal coverage campaigns. However, there is only limited info... Dennis J. Massue, Sarah J. Moore, Zawadi D. Mageni, Jason D. Moore, John Bradley, Olivier Pigeon, Erasto J. Maziba, Renata Mandike, Karen Kramer, William N. Kisinza, Hans J. Overgaard and Lena M. LorenzMalaria Journal201615:176 Malaria in pregnancy is an immense public health problem with at least 50 million pregnant women living in malaria endemic areas. To prevent malaria and its complications in pregnancy the World Health Organiza... Eric Bertrand Fokam, Leonard Ngimuh, Judith K. Anchang-Kimbi and Samuel WanjiMalaria Journal201615:172 A major goal in the search for new anti-malarial compounds is to identify new mechanisms of action or new molecular targets. While cell-based, growth inhibition-based screening have enjoyed tremendous success,... Vida Ahyong, Christine M. Sheridan, Kristoffer E. Leon, Jessica N. Witchley, Jonathan Diep and Joseph L. DeRisiMalaria Journal201615:173 Malaria is a public health concern in the French armed forces, with 400?800 cases reported every year and three deaths in the past 2 years. However, lack of chemoprophylaxis (CP) compliance is often reported a... Marie-Aude Créach, Guillaume Velut, Franck de Laval, Sébastien Briolant, Luc Aigle, Catherine Marimoutou, Xavier Deparis, Jean-Baptiste Meynard, Bruno Pradines, Fabrice Simon, Rémy Michel and Aurélie MayetMalaria Journal201615:174 María Fernández López, Jose Manuel Ruiz Giardín, Juan Víctor San Martín López, Jerónimo Jaquetti, Isabel García Arata, Carolina Jiménez Navarro and Noemi Cabello ClotetMalaria Journal201615:170 Arnold D. Forkuo, Charles Ansah, Kwesi M. Boadu, Johnson N. Boampong, Elvis O. Ameyaw, Ben A. Gyan, Andrea T. Arku and Michael F. OforiMalaria Journal201615:171 Construction sites are potential breeding places for some species of mosquitoes. Construction workers usually stay at the construction sites, thus being extremely susceptible to malaria. For malaria control, a... Siddharudha Shivalli, Sudarshan Pai, Kibballi Madhukeshwar Akshaya and Neevan D?SouzaMalaria Journal201615:168 There is growing interest in applying the sterile insect technique (SIT) against mosquitoes. Mass production of mosquitoes for large-scale releases demands a huge amount of water. Yet, many arid and/or seasona... Wadaka Mamai, Rosemary Susan Lees, Hamidou Maiga and Jeremie R. L. GillesMalaria Journal201615:169 There is an urgent need for vector control tools to supplement long-lasting insecticidal nets (LLINs) and indoor residual spraying; particularly in the Solomon Islands where the primary vector,Anopheles farauti,... Tanya L. Russell, Thomas R. Burkot, Hugo Bugoro, Allan Apairamo, Nigel W. Beebe, Weng K. Chow, Robert D. Cooper, Frank H. Collins and Neil F. LoboMalaria Journal201615:164 The production of properly folded, recombinant sub-unitPlasmodium falciparummalaria vaccine candidates in sufficient quantities is often a challenge. Success in vaccine immunogenicity studies in small animal mo... James M. Burns, Kazutoyo Miura, JoAnn Sullivan, Carole A. Long and John W. BarnwellMalaria Journal201615:159 Cerebral malaria remains a medical emergency with high mortality. Hypo-perfusion due to obstructed blood vessels in the brain is thought to play a key role in the pathophysiology of cerebral malaria leading to... Khalid Rehman, Ulrich Sauerzopf, Luzia Veletzky, Felix Lötsch, Mirjam Groger and Michael RamharterMalaria Journal201615:162 There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to determine the diagnostic accuracy of the NanoRam®, a handheld R... Benjamin J. Visser, Sophia G. de Vries, Emmanuel B. Bache, Janneke Meerveld-Gerrits, Daniëlle Kroon, Jimmy Boersma, Selidji T. Agnandji, Michèle van Vugt and Martin P. GrobuschMalaria Journal201615:160 Malaria hotspots, areas with consistently higher than average transmission, may become increasingly common as malaria declines. This phenomenon, currently observed in The Gambia, may be caused by several facto... Kevin Ochieng? Opondo, David Weetman, Musa Jawara, Mathurin Diatta, Amfaal Fofana, Florence Crombe, Julia Mwesigwa, Umberto D?Alessandro and Martin James DonnellyMalaria Journal201615:166 The pathogenesis of malaria is primarily associated with blood-stage infection and there is strong evidence that antibodies specific for parasite blood-stage antigens can control parasitaemia. This provides a ... Paola Favuzza, Simon Blaser, Anita M. Dreyer, Guy Riccio, Marco Tamborrini, Ralf Thoma, Hugues Matile and Gerd PluschkeMalaria Journal201615:161 Symptoms caused by bacterial, viral and malarial infections usually overlap and aetiologic diagnosis is difficult. Patient management in low-resource countries with limited laboratory services has been based p... Mercedes Rubio, Quique Bassat, Xavier Estivill and Alfredo MayorMalaria Journal201615:167 Experimental huts are simplified, standardized representations of human habitations that provide model systems to evaluate insecticides used in indoor residual spray (IRS) and long-lasting insecticidal nets (L... Dennis J. Massue, William N. Kisinza, Bernard B. Malongo, Charles S. Mgaya, John Bradley, Jason D. Moore, Filemoni F. Tenu and Sarah J. MooreMalaria Journal201615:165 The World Health Organization recommends malaria to be confirmed by either microscopy or a rapid diagnostic test (RDT) before treatment. The correct use of RDTs in resource-limited settings facilitates basing ... Alinune N. Kabaghe, Benjamin J. Visser, Rene Spijker, Kamija S. Phiri, Martin P. Grobusch and Michèle van VugtMalaria Journal2016 ?There is no free here,? the words of a Malian husband, illustrate how perceptions of cost can deter uptake of intermittent preventive treatment of malaria in pregnancy (IPTp). The Malian Ministry of Health (M... Meredith C. Klein, Steven A. Harvey, Hawa Diarra, Emily A. Hurley, Namratha Rao, Samba Diop and Seydou DoumbiaMalaria Journal201615:158 Concurrent malaria and arbovirus infections are common and represent an important public health concern in regions where both diseases are endemic. The present study investigates the genetic diversity and comp... Makhtar Niang, Cheikh Loucoubar, Abdourahmane Sow, Moussa Moise Diagne, Oumar Faye, Ousmane Faye, Mawlouth Diallo, Aissatou Toure-Balde and Amadou A. SallMalaria Journal201615:155 Malaria among school children is increasingly receiving attention, yet the burden of malaria in this age group is poorly defined. This study presents data on malaria morbidity among school children in Bungoma. Stella Kepha, Birgit Nikolay, Fred Nuwaha, Charles S. Mwandawiro, Joaniter Nankabirwa, Juliet Ndibazza, Jorge Cano, Damaris Matoke-Muhia, Rachel L. Pullan, Elizabeth Allen, Katherine E. Halliday and Simon J. BrookerMalar Jour2016 Avian malaria vector competence studies are needed to understand more succinctly complex avian parasite-vector-relations. The lack of vector competence trials may be attributed to the difficulty of obtaining g... Jenny S. Carlson, Federico Giannitti, Gediminas Valki?nas, Lisa A. Tell, Joy Snipes, Stan Wright and Anthony J. CornelMalaria Journal201615:154 The circumsporozoite protein is the most abundant polypeptide expressed by sporozoites, the malaria parasite stage capable of infecting humans. Sporozoite invasion of mosquito salivary glands prior to transmis... Bianca B. Kojin, André Luis Costa-da-Silva, Ceres Maciel, Dayane Alves Henriques, Danilo O. Carvalho, Kelcie Martin, Osvaldo Marinotti, Anthony A. James, Myrna C. Bonaldo and Margareth Lara CapurroMalaria Journal201615:153 The proportion of blood meals that mosquitoes take from a host species is a function of the interplay of extrinsic (abundance and location of potential hosts) and intrinsic (innate preference) factors. A mark-... Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Robert D. Cooper, Frank H. Collins, Neil F. Lobo and Thomas R. BurkotMalaria Journal201615:152 The effectiveness of vector control on malaria transmission by LLINs and IRS depends on the vectors entering houses to blood feed and rest when peopl... Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Weng K. Chow, Robert D. Cooper, Frank H. Collins, Neil F. Lobo and Thomas R. BurkotMalaria Journal201615:156 In the 1970s,An.farautiin the Solomon Island responded to indoor residual spraying with DDT by increasingly feeding more outdoors and earlier in the evening. Although long-lasting insecticidal nets (LLIN... Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Frank H. Collins, Robert D. Cooper, Neil F. Lobo and Thomas R. BurkotMalaria Journal2016 The host response to infection byP.falciparum, the parasite most often responsible for severe malaria, ranges from asymptomatic parasitaemia to death. The clinical trajectory of malaria is influenced by... Rafal S. Sobota, Antoine Dara, Jessica E. Manning, Amadou Niangaly, Jason A. Bailey,Abdoulaye K. Kone, Mahamadou A. Thera, Abdoulaye A. Djimdé, Guy Vernet, Philippe Leissner, Scott M. Williams, Christopher V. Plowe and Ogobara K. DoumboMalaria Journal201615:150 Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern province, Zambia a mass t... Erin M. Stuckey, John M. Miller, Megan Littrell, Nakul Chitnis and Rick SteketeeMalaria Journal201615:148 Plasmodium falciparumresistance to artemisinins, the most potent and fastest acting anti-malarials, threatens malaria elimination strategies.Artemisinin resistance is due to mutation of... Lucie Paloque, Arba P. Ramadani, Odile Mercereau-Puijalon, Jean-Michel Augereau and Françoise Benoit-VicalMalaria Journal201615:149 This article reports the changing pattern of US President?s Malaria Initiative-funded IRS in sub-Saharan Africa between 2008 and 2015. IRS coverage in sub-Saharan Africa increased from <2 % of the at-risk popu... Traditionally, it has taken decades to introduce new interventions in low-income countries. Several factors account for these delays, one of which is the absence of a framework to facilitate comprehensive unde...Idda Romore, Ritha J. A. Njau, Innocent Semali, Aziza Mwisongo, Antoinette Ba Nguz, Hassan Mshinda, Marcel Tanner and Salim AbdullaMalaria Journal201615:143 Sri Lanka is a malaria-free country. However it remains surrounded by countries with endemic malaria transmission. Since the last indigenous case of malaria was reported in October 2012, only imported malaria ... Sumadhya Deepika Fernando, Priyani Dharmawardana, Saveen Semege, Geetha Epasinghe, Niroshana Senanayake, Chaturaka Rodrigo and Risintha Premaratne Malaria Journal201615:144 Quantitative real-time PCR (qPCR) is now commonly used as a method to confirm diagnosis of malaria and to differentiate recrudescence from re-infection, especially in clinical trials and in reference laborator... Noemí Bahamontes-Rosa, Ane Rodriguez Alejandre, Vanesa Gomez, Sara Viera, María G. Gomez-Lorenzo, Laura María Sanz-Alonso and Alfonso Mendoza-LosanaMalaria Journal201615:147 This study was part of the work to prepare for a cluster-randomized controlled trial to evaluate the effect of combining indoor residual spraying and long-lasting insecticidal nets on malaria incidence. A pilo... Taye Gari, Oljira Kenea, Eskindir Loha, Wakgari Deressa, Alemayehu Hailu, Meshesha Balkew, Teshome Gebre-Michael, Bjarne Robberstad, Hans J. Overgaard and Bernt LindtjørnMalaria Journal201615:145 With the dramatic increase in international travel among Chinese people, the risk of malaria importation from malaria-endemic regions threatens the achievement of the malaria elimination goal of China. Zhongjie Li, Qian Zhang, Canjun Zheng, Sheng Zhou, Junling Sun, Zike Zhang, Qibin Geng, Honglong Zhang, Liping Wang, Shengjie Lai, Wenbiao Hu, Archie C. A. Clements, Xiao-Nong Zhou and Weizhong YangMalaria Journal201615:141 Malaria remains a heavy burden across sub-Saharan Africa where transmission is maintained by some of the world?s most efficient vectors. Indoor insecticide-based control measures have significantly reduced tra... Marianne E. Sinka, Nick Golding, N. Claire Massey, Antoinette Wiebe, Zhi Huang, Simon I. Hay and Catherine L. MoyesMalaria Journal2016 Europe once had widespread malaria, but today it is free from endemic transmission. Changing land use, agricultural practices, housing quality, urbanization, climate change, and improved healthcare are among t... Xia Zhao, David L. Smith and Andrew J. TatemMalaria Journal201615:122 Repeated exposure toPlasmodium falciparumis associated with perturbations in B cell sub-set homeostasis, including expansion atypical memory B cells. However, B cell perturbations immediately following acute ma... Richard T. Sullivan, Isaac Ssewanyana, Samuel Wamala, Felistas Nankya, Prasanna Jagannathan, Jordan W. Tappero, Harriet Mayanja-Kizza, Mary K. Muhindo, Emmanuel Arinaitwe, Moses Kamya, Grant Dorsey, Margaret E. Feeney, Eleanor M. Riley, Chris J. Drakeley and Bryan GreenhouseMalaria Journal201615:139 In 2013, the Zambian Ministry of Health through its NMCP distributed over two million insecticide-treated bed nets (ITNs) in four provinces using a door-to-door distribution strat... Paul Wang, Alison L. Connor, Ammar S. Joudeh, Jeffrey Steinberg, Ketty Ndhlovu, Musanda Siyolwe, Bristol Ntebeka, Benjamin Chibuye and Busiku HamainzaMalaria Journal2016 Patients? adherence to malaria treatment is a key issue in malaria control and elimination efforts. Previous studies have reported on problems with adherence to anti-malarials, which in part can be related to ...Joan Muela Ribera, Susanna Hausmann-Muela, Charlotte Gryseels and Koen Peeters GrietensMalaria Journal201615:136 In vitro drug susceptibility testing of malaria parasites remains an important component of surveillance for anti-malarial drug resistance. The half-maximal inhibition of growth (IC50) is the most commonly report... Grennady Wirjanata, Irene Handayuni, Sophie G. Zaloumis, Ferryanto Chalfein, Pak Prayoga, Enny Kenangalem, Jeanne Rini Poespoprodjo, Rintis Noviyanti, Julie A. Simpson, Ric N. Price and Jutta MarfurtMalaria Journal201615:137 Malaria re-introduction is a challenge in elimination settings. To prevent re-introduction, receptivity, vulnerability, and health system capacity of foci should be monitored using appropriate tools. This stud... Mansour Ranjbar, Alireza Shoghli, Goodarz Kolifarhood, Seyed Mehdi Tabatabaei, Morteza Amlashi and Mahdi MohammadiMalaria Journal201615:138 Detection ofPlasmodiumspp. is sometimes inconvenient especially in rural areas that are distant from a laboratory. In this study a portable diagnostic test ofPlasmodiumspp. was developed using insulated isoth... Kek Heng Chua, Ping Chin Lee and Hwa Chia ChaiMalaria Journal201615:134 The WHO recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme on immuniz... Katherine Theiss-Nyland, Waqo Ejersa, Corine Karema, Diakalia Koné, Hannah Koenker, Yves Cyaka, Matthew Lynch, Jayne Webster and Jo LinesMalaria Journal2016 As momentum towards malaria elimination grows, strategies are being developed for scale-up in elimination settings. one prominent strategy, reactive case detection (RACD), involves screening and treating indiv... John Hustedt, Sara E. Canavati, Chandary Rang, Ruth A. Ashton, Nimol Khim, Laura Berne, Saorin Kim, Siv Sovannaroth, Po Ly, Didier Ménard, Jonathan Cox, Sylvia Meek and Arantxa Roca-FeltrerMalaria Journal201615:132 Malaria is a mosquito-borne, lethal disease that affects millions and kills hundreds of thousands of people each year, mostly children. There is an increasing need for models of malaria control. In this paper,... Harry J. Dudley, Abhishek Goenka, Cesar J. Orellana and Susan E. MartonosiMalaria Journal201615:133 The Republic of Yemen has the highest incidence of malaria in the Arabian Peninsula, yet little is known of its vectors or transmission dynamics. Samira M. A. Al-Eryani, Louise Kelly-Hope, Ralph E. Harbach, Andrew G. Briscoe, Guy Barnish, Ahmed Azazy and Philip J. McCallMalaria Journal201615:130 Malaria transmission, primarily mediated byAn.gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding. New or improved vector control strateg... Victoria M. Mwakalinga, Benn K. D. Sartorius, Yeromin P. Mlacha, Daniel F. Msellemu, Alex J. Limwagu, Zawadi D. Mageni, John M. Paliga, Nicodem J. Govella, Maureen Coetzee, Gerry F. Killeen and Stefan DongusMalaria Journal2016 A three-day course of chloroquine remains a standard treatment ofPlasmodium vivaxinfection in Thailand with satisfactory clinical efficacy and tolerability although a continuous decline in in vitro parasite sen... Richard Höglund, Younis Moussavi, Ronnatrai Ruengweerayut, Anurak Cheomung, Angela Äbelö and Kesara Na-BangchangMalaria Journal201615:129 Recent data from Malawi suggest that school-aged children (SAC), aged 5?15 years, have the highest prevalence ofP.falciparuminfection among all age groups. They are the least likely group to utilize in... Andrea G. Buchwald, Jenny A. Walldorf, Lauren M. Cohee, Jenna E. Coalson, Nelson Chimbiya, Andy Bauleni, Kondwani Nkanaunena, Andrew Ngwira, Atupele Kapito-Tembo, Don P. Mathanga, Terrie E. Taylor and Miriam K. LauferMalaria Journal2016 Nested PCRs based on thePlasmodium18s-rRNA gene have been extensively used for human malaria diagnosis. However, they are not practical when large quantities of samples need to be processed, further there have ... Diego F. Echeverry, Nicholas A. Deason, Jenna Davidson, Victoria Makuru, Honglin Xiao, Julie Niedbalski, Marcia Kern, Tanya L. Russell, Thomas R. Burkot, Frank H. Collins and Neil F. LoboMalaria Journal201615:128 Rapid diagnostic Tests (RDTs) for malaria enable diagnostic testing at primary care facilities in resource-limited settings, where weak infrastructure limits the use of microscopy. In 2010, Ghana adopted a tes... Nana Yaa Boadu, John Amuasi, Daniel Ansong, Edna Einsiedel, Devidas Menon and Stephanie K. YanowMalaria Journal201615:126 Differences in parasite transmission intensity influence the process of acquisition of host immunity toP.falciparummalaria and ultimately, the rate of malaria related morbidity and mortality. Potentia... Bright Adu, Mariama K. Cherif, Samuel Bosomprah, Amidou Diarra, Fareed K. N. Arthur, Emmanuel K. Dickson, Giampietro Corradin, David R. Cavanagh, Michael Theisen, Sodiomon B. Sirima, Issa Nebie and Daniel DodooMalaria Journal2016 The use of ACT as first-line treatment for uncomplicated malaria was a policy recommended by World Health Organization. In 2004, Ghana changed her first-line anti-malari... Samuel Chatio, Raymond Aborigo, Philip Baba Adongo, Thomas Anyorigiya, Philip Ayizem Dalinjong, Patricia Akweongo and Abraham OduroMalaria Journal201615:125 India contributes 1.5?2 million annual confirmed cases of malaria. Since both parasites and vectors are evolving rapidly, updated information on parasite prevalence in mosquitoes is important for vector manage... Ashwani Kumar, Rajeshwari Hosmani, Shivaji Jadhav, Trelita de Sousa, Ajeet Mohanty, Milind Naik, Adarsh Shettigar, Satyajit Kale, Neena Valecha, Laura Chery and Pradipsinh K. RathodMalaria Journal201615:124 The Global Fund to Fight AIDS, Tuberculosis, and Malaria (GFATM) has been the largest financial supporter of malaria since 2002. In 2011, the GFATM transitioned to a new funding model (NFM), which prioritizes ...Brittany Zelman, Melissa Melgar, Erika Larson, Allison Phillips and Rima ShrettaMalaria Journal201615:118 Countries of the greater Mekong subregion have made a transition from malaria control to an aim for falciparum and vivax malaria elimination. The elimination of falciparum malaria will have to be achieved agai... Sara E. Canavati, Harriet L. S. Lawford, Bayo S. Fatunmbi, Dysoley Lek, Narann Top-Samphor, Rithea Leang, Arjen M. Dondorp, Rekol Huy and Walter M. KazadiMalaria Journal201615:120 Combination therapy with artesunate plus SP was adopted as recommended treatment forP.falciparuminfection in Afghanistan in 2003. Ghulam Rahim Awab, Mallika Imwong, Sasithon Pukrittayakamee, Fazel Alim, Warunee Hanpithakpong, Joel Tarning, Arjen M. Dondorp, Nicholas P. J. Day, Nicholas J. White and Charles J. WoodrowMalaria Journal201615:121 The US FDA recently developed CD3+, a counterfeit detection tool that is based on sample illumination at specific wavelengths of light and visual comparison of suspect sample and packaging materials to an auth... JaCinta S. Batson, Daniel K. Bempong, Patrick H. Lukulay, Nicola Ranieri, R. Duane Satzger and Leigh VerboisMalaria Journal201615:119 P.vivaxmalaria is a major public health problem in India. Control of vivax malaria is challenging due to various factors including relapse which increase the burden significa... Ram Das, Ramesh C. Dhiman, Deepali Savargaonkar, Anupkumar R. Anvikar and Neena ValechaMalaria Journal201615:115 ACT has been first-line treatment for falciparum malaria in Myanmar since 2005. The wide extent of artemisinin resistance in the Greater Mekong sub-region and the presence of ... Aye A. Win, Mallika Imwong, Myat P. Kyaw, Charles J. Woodrow, Kesinee Chotivanich, Borimas Hanboonkunupakarn and Sasithon PukrittayakameeMalaria Journal201615:110 Malaria is one of the most lethal and life-threatening infectious diseases in the world, causing more than half a million deaths annually. Treatment with mefloquine and artesunate is currently recommended by t...Breno Maurício Marson, Raquel de Oliveira Vilhena, Camilla Regina de Souza Madeira, Flávia Lada Degaut Pontes, Mário Sérgio Piantavini and Roberto PontaroloMalaria Journal201615:109 The Malaria Policy Advisory Committee (MPAC) to the World Health Organization held its eighth meeting in Geneva, Switzerland from 16 to 18 September 2015. This article provides a summary of the discussions, co...Malaria Journal201615:117 Malaria remains a major public health threat accounting for 30.4 % of disease morbidity in outpatient clinic visits across all age groups in Uganda. Consequently, malaria control remains a major public health ... Charles Bawate, Sylvia T. Callender-Carter, Ben Nsajju and Denis BwayoMalaria Journal201615:112 Conventional malaria parasite detection methods, such as RDT and light microscopy (LM), are not sensitive enough to detect low level parasites and identification of gametocytes in the ... Deborah Sumari, Brian T. Grimberg, D?Arbra Blankenship, Joseph Mugasa, Kefas Mugittu, Lee Moore, Paul Gwakisa and Maciej ZborowskiMalaria Journal201615:113 Emergence of drug-resistantPlasmodium falciparumhas created an urgent need for new drug targets. DNA polymerase ? is an essential enzyme required for chromosomal DNA replication and repair, and therefore may be... Jitlada Vasuvat, Atcha Montree, Sangduen Moonsom, Ubolsree Leartsakulpanich, Songsak Petmitr, Federico Focher, George E. Wright and Porntip Chavalitshewinkoon-PetmitrMalaria Journal201615:116 Plasmodiuminvasion of the mosquito midgut is a population bottleneck in the parasite lifecycle. Interference with molecular mechanisms by which the ookinete invades the mosquito midgu... Fengwu Li, Viengngeun Bounkeua, Kenneth Pettersen and Joseph M. VinetzMalaria Journal201615:111 Deforestation and land-use change have the potential to alter human exposure to malaria. A large percentage of Madagascar?s original forest cover has been lost to slash-and-burn agriculture, and malaria is one... Sarah Zohdy, Kristin Derfus, Emily G. Headrick, Mbolatiana Tovo Andrianjafy, Patricia C. Wright and Thomas R. GillespieMalaria Journal201615:114 Malaria accounts for many deaths and illnesses, mostly among young children and pregnant women in sub-Saharan Africa. An integrated approach is recommended to ensure effective malaria control. Socio-cultural f... Lawrence G. Febir, Kwaku Poku Asante, Samuel Afari-Asiedu, Livesy N. Abokyi, Anthony Kwarteng, Bernhards Ogutu, Margaret Gyapong and Seth Owusu-AgyeiMalaria Journal201615:108 In the Amhara Region of Ethiopia, a steep decline of malaria cases was seen in early 2014. This study verified the decrease of the malaria cases along with the positivity rates among acute febrile illness pati... Yumi Toyama, Masaki Ota, Getinet Molla and Belay Bezabih Beyene Malaria Journal201615:104 The fight against malaria is increasingly threatened by failures in vector control due to growing insecticide resistance. This review examines the recent primary research that addresses the putative relations... Molly C. Reid and F. Ellis McKenzieMalaria Journal201615:107 Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all fivePlasmodiumparasites causing disease in humans.Although not included in the World Health Organization crit... Spinello Antinori, Alberto Corona, Anna Lisa Ridolfo, Laura Galimberti, Davide Ricaboni, Laura Milazzo and Mario CorbellinoMalaria Journal2016 In a context of large-scale implementation of malaria vector control tools, such as the distribution of long-lasting insecticide nets (LLIN), it is necessary to regularly assess whether strategies are progress... Georgia Barikissou Damien, Armel Djènontin, Evelyne Chaffa, Sandra Yamadjako, Papa Makhtar Drame, Emmanuel Elanga Ndille, Marie-Claire Henry, Vincent Corbel, Franck Remoué and Christophe RogierMalaria Journal201615:102 A number of experiments have previously indicated thatPlasmodium falciparum-infected erythrocytes (pRBC) were able to sense host environment. The basis of this ability to detect external cues is not known but in... Yang Wu, Laura N. Cruz, Tadge Szestak, Gavin Laing, Gemma R. Molyneux, Celia R. S. Garcia and Alister G. CraigMalaria Journal201615:103 A key goal of malaria control is to achieve universal access to, and use of, LLINs among people at risk for malaria. Quantifying the number of LLINs needed to achieve and maint... Kathrine R. Tan, Jane Coleman, Barbara Smith, Busiku Hamainza, Cecilia Katebe-Sakala, Casey Kean, Ashley Kowal, Jodi Vanden Eng, Tiffany K. Parris, Carla T. Mapp, Stephen C. Smith, Robert Wirtz, Mulakwa Kamuliwo and Allen S. CraigMalaria Journal201615:106 Plasmodium vivaxis the most widely distributed species causing the highest number of malaria cases in the world. In Brazil,P. vivaxis responsible for approximately 84 % of reported.Larissa Rodrigues Gomes, Natália Ketrin Almeida-de-Oliveira, Aline Rosa de Lavigne, Suelen Rezende Félix de Lima, Anielle de Pina-Costa, Patrícia Brasil, Cláudio Tadeu Daniel-Ribeiro, Didier Ménard and Maria de Fatima Ferreira-da-CruzMalaria Journal201615:96 RDTs play a key role in malaria management and control. The PfHRP-2 based RDT is the most widely used RDT for malaria diagnosis in Ghana. Deletion ofpfhrp2 inP.falcipar...Linda Eva Amoah, Joana Abankwa and Akua OppongMalaria Jour2016 Tafenoquine (TQ) and primaquine (PQ) are 8-aminoquinolines (8-AQ) with anti-hypnozoite activity against vivax malaria. PQ is the only FDA-approved medicine for preventing relapsingP.vivaxinfection and ... Pamela L. St Jean, Zhengyu Xue, Nick Carter, Gavin C. K. W. Koh, Stephan Duparc, Maxine Taylor, Claire Beaumont, Alejandro Llanos-Cuentas, Ronnatrai Rueangweerayut, Srivicha Krudsood, Justin A. Green and Justin P. RubioMalaria Journal2016 LLINs and IRS are the most widely accepted and applied malaria vector control methods. However, evidence that incremental impact is achieved when th... Busiku Hamainza, Chadwick H. Sikaala, Hawela B. Moonga, Javan Chanda, Dingani Chinula, Mulenga Mwenda, Mulakwa Kamuliwo, Adam Bennett, Aklilu Seyoum and Gerry F. KilleenMalaria Journal201615:100 Insecticide resistance seriously threatens the efficacy of vector control interventions in malaria endemic countries. In Afghanistan, the status of insecticide resistance is largely unknown while distribution ...Mushtaq Ahmad, Cyril Buhler, Patricia Pignatelli, Hilary Ranson, Sami Mohammad Nahzat, Mohammad Naseem, Muhammad Farooq Sabawoon, Abdul Majeed Siddiqi and Martijn VinkMalaria Journal201615:98 Pregnancy has been reported to alter the pharmacokinetic properties of anti-malarial drugs, including the different components of artemisinin-based combination therapy (ACT). However, small sample sizes make i...Renée J. Burger, Benjamin J. Visser, Martin P. Grobusch and Michèle van VugtMalaria Journal201615:99 Malaria remains one of the most prevalent tropical and infectious diseases in the world, with an estimated more than 200 million clinical cases every year. In recent years, the mosquito stages of the parasite ... Daniel Gonçalves and Patrick HunzikerMalaria Journal201615:95 Artemisinin-based combination therapy is recommended to treatPlasmodium falciparumworldwide, but observations of longer artemisinin (ART) parasite clearance times (PCTs) in Southeast Asia are widely interpreted... Whitney A. Kite, Viviana A. Melendez-Muniz, Roberto R. Moraes Barros, Thomas E. Wellems and Juliana M. SáMalaria Journal201615:94
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