Researchers have demonstrated in a clinical trial that a new vaccine for malaria has been up to 100 percent effective when assessed at 10 weeks after last dose of vaccine.

Researchers have identified gene expression signatures in the blood of RTS,S-vaccinated volunteers, which predict the likelihood of infection after exposure to parasite-carrying mosquitoes.

The United States eradicated malaria by spraying mosquito breeding grounds with DDT in 1951, roughly two decades after most of Western Europe eliminated the disease.

May 25, 2016 - The malaria parasite Plasmodium falciparum hijacks an immune system process to invade red blood cells, according to a study led by researchers at Penn State College of Medicine. Understanding how malaria invades the cells could lead to a more effective vaccine.

The vaccine candidate is the first in-human study of its kind under an investigational new drug application with the US FDA.

• Pilot implementation of first malaria vaccine recommended by WHO advisory groups (11/05/2015)
• Malaria vaccine: How good is good enough? (07/25/2015)
• Malaria vaccine gets 'green light' (07/25/2015)
• 'Pretty Good' Malaria Vaccine Moves Forward (07/31/2014)
• UK firm seeks to market world's first malaria vaccine (10/31/2013)