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Những ấn phẩm khoa học mới về nghiên cứu sốt rét
Cho đến nay sốt rét vẫn là một trong những căn bệnh gây tử vong hàng đầu trong số các bệnh truyền nhiễm trên toàn thế giới, nên các kinh phí và nguồn lực hiện đã và đang tiếp tục đầu tư nghiên cứu cả cơ bản và cả nghiên cứu chuyen sâu ứng dụng vào lĩnh vực sốt rét, cả về sinh bệnh học, chẩn đoán, điều trị và thuốc sốt rét mới. Ban Biên tập Website xin chuyển đến quý bạn đồng nghiệp những ấn phẩm mới về nghiên cứu thời gian gần đây. Thành quả của Chương trình quốc gia phòng chống sốt rét (PCSR) đạt được nhờ vào sự can thiệp tổng hòa các biện pháp phòng chống vector, vai trò điều tra dịch tễ chỉ đạo, phát hiện sớm và điều trị kịp thời, nghĩa là không thể không kể đến hiệu quả thuốc sốt rét. Giám sát thường quy và chặt chẽ tình hình kháng thuốc để trên cơ sở đó đề xuất các phác đồ điều trị sốt rét có hiệu quả và quản lý ca bệnh kịp thời là một trong những điểm chính yếu làm giảm sốt rét. Từ năm 1990, thuốc chống sốt rét artemisinine và dẫn chất artesunate được tiến hành thử nghiệm lâm sàng và chính thức đưa vào sử dụng rộng rãi trong Chương trình PCSR ở nước ta đã có vai trò quan trọng trong trong việc hạ thấp tỷ lệ bệnh và tỷ lệ tử vong do sốt rét. Mặc dù với liệu trình 5 ngày, tỷ lệ khỏi bệnh do sốt rét P. falciparum có thể đến 80-90%, nhưng nhược điểm lớn nhất của artemisinine/artesunate điều trị đơn thuần là tỷ lệ tái phát sớm sau điều trị quá cao (35-50%) hoặc 7-50%; để khắc phục nhược điểm này, nhiều phác đồ điều trị sốt rét phối hợp có gốc artemisinine hoặc dẫn suất (ACTs_Artemisinine-based Combination Therapies) đã được nghiên cứu sử dụng ở nhiều nước trên thế giới, trong đó có Việt Nam như thuốc như thuốc CV-8 [Dihydroartemisinie + Piperaquine phosphate + Primaquine phosphate + Trimethoprim], Artekin, Arterakine, CV Artecan [Dihydroartemisinie 40mg + Piperaquine phosphate 320mg] và Artequick 2 thành phần [Artemisinine + Piperaquine phosphate], gần đây có Artequick hoặc Artequick-primaquine gồm 2 hoặc 3 thành phần [Artemisinie 40mg + Piperaquine 188mg + primaquine 2mg], Coarsucam hay Winthrop [Artesunate + Amodiaquine]. Hiện tại hơn 72 quốc gia trên thế giới theo khuyến cáo dùng thuốc ACTs như lựa chọn ưu tiên để điều trị P.falciparum.
1. Research: Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixedspecies malaria in Gabon Ghyslain Mombo-Ngoma, Christian Kleine, Arti Basra, Heike Würbel, Daisy A Diop, Mesküre Capan, Ayola A Adegnika, Florian Kurth, Benjamin Mordmüller, Fanny Joanny, Peter G Kremsner, Michael Ramharter, Sabine Bélard Malaria Journal 2012, 11:120 (19 April 2012) Abstract | Provisional PDF | Editor’s summary A useful report covering a neglected aspect of anti-malarial treatment- how to deal with non-falciparum infection and the role of ACT.
2. Methodology: Comparison of molecular tests for the diagnosis of malaria in Honduras Gustavo A Fontecha, Meisy Mendoza, Engels Banegas, Mitra Poorak, Alexandre M De Oliveira, Tamara Mancero, Venkatachalam Udhayakumar, Naomi W Lucchi, Rosa E Mejia Malaria Journal 2012, 11:119 (18 April 2012) Abstract | Provisional PDF | Editor’s summary The authors compared four new single reaction amplification protocols aimed at detecting P. falciparum, P. vivax, or both, with a standard nested PCR protocol. The data obtained indicated that some protocols but not others equal the sensitivity of the nested PCR, and in particular for the detection of the minor species in a mixed infection.
3. Research Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission Bernadette J Huho, Gerard F Killeen, Heather M Ferguson, Adriana Tami, Christian Lengeler, J Derek Charlwood, Anisette Kihonda, Japhet Kihonda, S Patrick Kachur, Thomas A Smith, Salim M Abdulla Malaria Journal 2012, 11:118 (18 April 2012) Abstract | Provisional PDF | Editor’s summary A study of the impact of artesunate/SP use on oocyst/sporozoite carriage in mosquitoes. It is not unexpected that in an area of intense malaria transmission, with presumed large numbers of asymptomatic gametocyte carriers, that ACT does not result in a marked reduction in transmission indices. Whilst the result in not unexpected the methodology is thorough and is likely to be useful to others.
4. Research Can slide positivity rates predict malaria transmission? Yan Bi, Wenbiao Hu, Huaxin Liu, Yujiang Xiao, Yuming Guo, Shimei Chen, Laifa Zhao, Shilu Tong Malaria Journal 2012, 11:117 (18 April 2012) Abstract | Provisional PDF | Editor’s summary The authors suggest that slide positivity rates are strongly correlated with the malaria incidence and in this particular setting this explains most of the variation in malaria transmission.
5. Research Investigations on anopheline mosquitoes close to the nest sites of chimpanzees subject to malaria infection in Ugandan Highlands Sabrina Krief, Florence Levrero, Jean-Michel Krief, Supinya Thanapongpichat, Mallika Imwong, Georges Snounou, John M Kasenene, Marie Cibot, Jean-Charles Gantier Malaria Journal 2012, 11:116 (17 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Presents data on Anopheles mosquitoes captured near chimpanzee habitats in the western highlands of Uganda. It documents some environmental characteristics associated with some of the ten species that were found, most in very low abundance. None of the mosquitoes were infected with Plasmodium spp. The background review and findings from other reports presented in the discussion are thorough and well documented.
6. Research
Analysis for genotyping Duffy blood group in inhabitants of Sudan, the Fourth Cataract of the Nile Agnieszka Kempinska-Podhorodecka, Oktawian Knap, Arleta Drozd, Mariusz Kaczmarczyk, Miroslaw Parafiniuk, Milosz Parczewski, Andrzej Ciechanowicz Malaria Journal 2012, 11:115 (17 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Interesting observation of unique Duffy-negative Shagia and Manasir ethnicities of Sudan.
7. Review
The epidemiology of postpartum malaria: a systematic review Machteld E Boel, Marcus J Rijken, Bernard J Brabin, Francois Nosten, Rose McGready Malaria Journal 2012, 11:114 (13 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The major findings of this review are a decrease in the risk of malaria infection after delivery (compared to the gestational period), but still a higher risk in the postpartum compared to non-pregnant controls. The authors discuss the protection conferred in the postpartum by IPTp or chemoprophylaxis, and the risk of recrudescence of resistant parasites due to inadequate treatment in the gestational period.
8. Research Molecular monitoring of Plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaounde, Cameroon: Implications for the future Sandie Menard, Isabelle Morlais, Rachida Tahar, Collins Sayang, Pembe Issamou Mayengue, Xavier Iriart, Francoise Benoit-Vical, Brigitte Lemen, Jean-Francois Magnaval, Parfait Awono-Ambene, Leonardo K Basco, Antoine Berry Malaria Journal 2012, 11:113 (12 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary This study represents a survey of molecular markers related to drug resistance in a series of samples collected between 2005 and 2009.
9. Research
Imported malaria in pregnancy in Madrid Beatriz C Jimenez, Pedro Cuadros-Tito, Jose M Ruiz-Giardin, Gerardo Rojo-Marcos, Juan Cuadros-Gonzalez, Eduardo Canalejo, Noemi Cabello, Juan V San Martin, Ana M Barrios, Juan Hinojosa, Laura Molina Malaria Journal 2012, 11:112 (11 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary There was clearly a need to bring more attention to the issue of malaria in pregnancy in non-endemic areas is relevant. This is a retrospective descriptive study of laboratory-confirmed malaria in 19 pregnant women.
10. Research
Pfatp6 molecular profile of Plasmodium falciparum isolates in the western Brazilian Amazon Larissa W Brasil, Andre L.L. Areas, Gisely C Melo, Cintia MC Oliveira, Maria GC Alecrim, Marcus VG Lacerda, Connor O'Brien, Walter MR Oelemann, Mariano G Zalis Malaria Journal 2012, 11:111 (10 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Report describing the partial analysis of the pfatp6 gene in 60 P. falciparum isolates collected during a period of a decade.
11. Research
Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana Eili Y Klein, Ian A Lewis, Christina Jung, Manuel Llinas, Simon A Levin Malaria Journal 2012, 11:110 (6 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary In a study of drug quality in Ghana, surprisingly, quality was found to be uniformly high ( of 33 drugs collected from 16 different shops, only one contained less than 80% of its purported active ingredient), and thus no significant relationship between price, treatment-seeking behaviour and the content of the active ingredients was observed. However, artemisinin monotherapy, which the WHO considers inappropriate therapy, was still widely available in Ghana in 2010.
12. Research
Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali Stephanie Bostrom, Pablo Giusti, Charles Arama, Jan-Olov Persson, Victor Dara, Boubacar Traore, Amagana Dolo, Ogobara Doumbo, Marita Troye-Blomberg Malaria Journal 2012, 11:109 (5 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The paper describes the levels of several different mediators (cytokines, chemokines) and parasite-specific antibody responses in Fulani and Dogon children.
13.Research
Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso Alexandre Atkinson, Severine Garnier, Sarwat Afridi, Francis Fumoux, Pascal Rihet Malaria Journal 2012, 11:108 (4 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Cell-biological data suggest the role of heparan sulphate in many of the interactions of the parasite with the host, including cell-surfaces, serum-proteins and cytokines.This study looked at the presence of SNPs in the genes involved in O-sulphation of HS.
14. Case report
A histopathologic study of fatal paediatric cerebral malaria caused by mixed Plasmodium falciparum/Plasmodium vivax infections Laurens Manning, Anna Rosanas-Urgell, Moses Laman, Henry Edoni, Catriona McLean, Ivo Mueller, Peter Siba, Timothy ME Davis Malaria Journal 2012, 11:107 (3 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The paper investigate the underlying pathophysiology of P. vivax in three children dying from severe malarial coma. The authors conclude that the lack of evidence of P. vivax sequestration in the brain patients argues against the role of this process in the pathogenesis of vivax coma.
15. Opinion
Selection of mosquito life-histories: a hidden weapon against malaria? Heather M Ferguson, Nicholas Maire, Willem Takken, Issa N Lyimo, Olivier Briet, Steve W Lindsay, Thomas A Smith Malaria Journal 2012, 11:106 (3 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The paper puts forward the hypothesis that a small reduction in Africa-wide mosquito survival that is attributable to widespread ITN deployment is responsible for the decline in malaria transmission rates across the continent.
16. Research
Genetic polymorphism of merozoite surface protein 2 and prevalence of K76T pfcrt mutation in Plasmodium falciparum field isolates from Congolese children with asymptomatic infections Felix Koukouikila-Koussounda, Vladimir Malonga, Pembe Issamou Mayengue, Mathieu Ndounga, Christevy Jeannhey Vouvoungui, Francine Ntoumi Malaria Journal 2012, 11:105 (1 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The paper describes a study on the molecular epidemiology of Plasmodium falciparum infections in asymptomatic children in Brazzaville, after the introduction of ACT four years prior to the study.The authors conclude that the results reflect reduced transmission and that chloroquine cannot be reintroduced as anti-malarial in the country.
17. Research
Plasmodium yoelii blood-stage primes macrophage-mediated innate immune response through modulation of toll-like receptor signalling Yong Fu, Yan Ding, Taoli Zhou, Xiaolan Fu, Wenyue Xu Malaria Journal 2012, 11:104 (1 April 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Innate response of macrophages in response to P. yoelii infected red blood cells. Both strains could enhance the response of peritoneal macrophages, through up-regulating the expression of TLR2 and intracellular signalling molecules.
18. Methodology
Improved negative selection protocol for Plasmodium berghei in the rodent malarial model Rachael Y Orr, Nisha Philip, Andrew P Waters Malaria Journal 2012, 11:103 (31 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The oral delivery of the negative selectable marker drug 5FC is just as efficient as the intraperitoneal injection. The authors make a point that using this method reduces animal numbers and animal handling.
19. Research
Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium Annemarie R Kreeftmeijer-Vegter, Perry J van Genderen, Leo G Visser, Wouter FW Bierman, Jan Clerinx, Cees KW van Veldhuizen, Peter J de Vries Malaria Journal 2012, 11:102 (31 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Data from the named patient programme demonstrate that IV artesunate is effective and well-tolerated in European travellers lacking immunity. However, increased attention needs to be paid to the possible development of haemolytic anaemia two or three weeks after start of treatment.
20. Research
Operational research to inform a sub-national surveillance intervention for malaria elimination in Solomon Islands Jo-An Atkinson, Marie-Louise Johnson, Rushika Wijesinghe, Albino Bobogare, L Losi, Matthew O'Sullivan, Yuka Yamaguchi, Geoffrey Kenilorea, Andrew Vallely, Qin Cheng, Andrew Ebringer, Lisa Bain, Karen Gray, Ivor Harris, Maxine Whittaker, Heidi Reid, Archie Clements, Dennis Shanks Malaria Journal 2012, 11:101 (30 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary A timely study that provides valuable lessons for intervention leading up to malaria elimination. The fact that surveillance efforts will not be easy - even on an island - challenge all in the malaria community to think about realistic targets - especially in light of the higher that previously estimated levels of malaria mortality.
21. Research
Molecular markers in Plasmodium falciparum linked to resistance to anti-malarial drugs in samples imported from Africa over an eight-year period (2002-2010): impact of the introduction of artemisinin combination therapy Aranzazu Amor, Carlos Toro, Amalia Fernandez-Martinez, Margarita Baquero, Agustin Benito, Pedro Berzosa Malaria Journal 2012, 11:100 (30 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary Molecular markers related to P falciparum resistance were analysed for the period of transition from SP to ACT, in isolates imported from Africa.
22. Research
The effect of household heads training on long-lasting insecticide-treated bed nets utilization: a cluster randomized controlled trial in Ethiopia Amare Deribew, Zewude Birhanu, Lelisa Sena, Tariku Dejene, Ayalu A Reda, Morankar Sudhakar, Fessehaye Alemseged, Fasil Tessema, Ahmed Zeynudin, Sibhatu Biadgilign, Kebede Deribe Malaria Journal 2012, 11:99 (30 March 2012) Abstract | Provisional PDF | PubMed
23. Research
Assessment of the risk of malaria re-introduction in the Maremma Plain (Central Italy) using a multi-factorial approach Roberto Romi, Daniela Boccolini, Roberto Vallorani, Francesco Severini, Luciano Toma, Maurizio Cocchi, Angelo Tamburro, Gianni Messeri, Antonio Crisci, Luca Angeli, Roberto Costantini, Irene Raffaelli, Giorgio Pontuale, Isabelle Thiery, Annie Landier, Gilbert Le Goff, Anna Maria Fausto, Marco Di Luca Malaria Journal 2012, 11:98 (30 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The manuscript presents a longitudinal study, which is of importance, more specifically now with the re-emergence of malaria in Greece of P. vivax and the threat for Southern Europe. The study details the main parameters to consider for the risk assessment: receptivity, susceptibility and vulnerability focussing on An. labranchiae potential vector for P. falciparum in Maremma area.
24. Research
Artesunate-amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India Anupkumar R Anvikar, Bhawna Sharma, Bharatendu H Shahi, Prajesh K Tyagi, Tarit K Bose, Surya K Sharma, Prakriti Srivastava, Bina Srivastava, Jean R Kiechel, Aditya P Dash, Neena Valecha Malaria Journal 2012, 11:97 (30 March 2012) Abstract | Provisional PDF | PubMed | Editor’s summary The fixed dose combination of ASAQ was found to be efficacious and safe treatment for P. falciparum malaria. The trial provides a sound basis for the use of the combination, once India opts for fixed dose combination ACT.
25. Research
Severe imported malaria in an intensive care unit: a review of 59 cases Lurdes C Santos, Candida F Abreu, Sandra M Xerinda, Margarida Tavares, Raquel Lucas, Antonio C Sarmento Malaria Journal 2012, 11:96 (29 March 2012)
Journal Watch 1.A Major Genome Region Underlying Artemisinin Resistance in Malaria. Cheeseman IH et al. Science. 6 April 2012;336(6077):79-82. DOI: 10.1126/science.1215966. [Abstract] (Added Apr 9, 2012) 2.Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study.Phyo AP et al. The Lancet. 5 April 2012. doi:10.1016/S0140-6736(12)60484-X. [Full Text] (Added Apr 9, 2012) 3.Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum.Augagneur Y et al. PNAS. April 2, 2012. doi: 10.1073/pnas.1203516109 [Abstract] (Added Apr 4, 2012) 4.Risk factors for mortality from imported falciparum malaria in the United Kingdom over 20 years: an observational study. Checkley AM et al. BMJ 2012;344. doi: 10.1136/bmj.e2116[Full Text] | Elderly are almost 10 times more likely to die of malaria than younger tourists BMJ Press Release. Mar 27, 2012[Full Text] (Added Apr 1, 2012) 5.Global malaria mortality between 1980 and 2010: a systematic analysis Murray CJL et al. The Lancet. 4 February 2012;379(9814):413-431. doi:10.1016/S0140-6736(12)60034-8 [Full Text] | New estimates of malaria deaths: concern and opportunity The Lancet Editorial. 4 February 2012;379(9814):385. doi:10.1016/S0140-6736(12)60169-X [Full Text] (Added Feb 3, 2012) 6.Evaluation of the antiplasmodial and cytotoxicity potentials of husk fiber extracts from Cocos nucifera, a medicinal plant used in Nigeria to treat human malaria Adebayo JO, Santana AEG, Krettli AU. Hum Exp Toxicol. January 12, 2012 0960327111424298 doi: 10.1177/0960327111424298 [Abstract] (Added Feb 3, 2012) 7.A new world malaria map: Plasmodium falciparum endemicity in 2010. Gething PW et al. Malaria Journal 2011;10:378 doi:10.1186/1475-2875-10-378 [Abstract] (Added Jan 25, 2012) 8.Endoplasmic Reticulum PI(3)P Lipid Binding Targets Malaria Proteins to the Host Cell. Souvik Bhattacharjee, Robert V. Stahelin, Kaye D. Speicher, David W. Speicher, Kasturi Haldar. Cell. 20 January 2012;148(1):201-212. [Abstract] (Added Jan 22, 2012) 9.Structure of a Potential Antimalarial Drug Target Revealed?: Structure and Reaction Mechanism of Phosphoethanolamine Methyltransferase from Malaria Parasite Plasmodium falciparum. Antiparasitic Drug Target. J. Biol. Chem. 2012;287:1435. [Full Text] (Added Jan 21, 2012) 10.Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic review and meta-analysis. Obonyo CO, Juma EA. Malaria Journal 2012;11:2. doi:10.1186/1475-2875-11-2 [Full Text] (Added Jan 21, 2012) 11.The Use of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax Malaria. Bassat Q. 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PLoS onE 2011;6(8):e24147. doi:10.1371/journal.pone.0024147 [Full Text] (Added Oct 27, 2011) 19.Laboratory demonstration of a prozone-like effect in HRP2-detecting malaria rapid diagnostic tests: implications for clinical management Jennifer Luchavez et al. Malaria Journal 2011;10:286 doi:10.1186/1475-2875-10-286 [Full Text] (Added Oct 9, 2011) 20.Dramatic Decrease in Malaria Transmission after Large-Scale Indoor Residual Spraying with Bendiocarb in Benin, an Area of High Resistance of Anopheles gambiae to Pyrethroids Martin Akogbeto et al. Am J Trop Med Hyg 2011;85(4):86-593. doi: 10.4269/ajtmh.2011.10-0668 [Abstract] (Added Oct 9, 2011) 21.Net Benefits: A Multicountry Analysis of Observational Data Examining Associations between Insecticide-Treated Mosquito Nets and Health Outcomes. Lim SS, Fullman N, Stokes A, Ravishankar N, Masiye F, et al. PLoS Med 2011; 8(9):e1001091. doi:10.1371/journal.pmed.1001091. [Full Text] (Added Sep 17, 2011) 22.Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum. Yeh E, DeRisi JL. PLoS Biol 2011;9(8): e1001138. doi:10.1371/journal.pbio.1001138 [Full Text] (Added Sep 5, 2011) 23.Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study. Trape JF et al. The Lancet Infectious Diseases. 18 August 2011. doi:10.1016/S1473-3099(11)70194-3 [Full Text] (Added Aug 22, 2011) 24.Rerooting the evolutionary tree of malaria parasites. Outlaw DC, Ricklefs RE. PNAS August 9, 2011;108(32):13183-13187 doi: 10.1073/pnas.1109153108 [Abstract] (Added Aug 12, 2011) 25.Resolving the phylogeny of malaria parasites. Rich SM, Xu G. 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Journal of Infection and Public Health June 2011;4(2):91-95[Abstract] (Added June 18, 2011) 30.Safety, pharmacokinetics and efficacy of artemisinins in pregnancy Veronica Ades. Infectious Disease Reports 2011;3(1)37-43 [Full text] (Added June 18, 2011) 31.Prozone in malaria rapid diagnostics tests: how many cases are missed? Philippe Gillet et al. Malaria Journal 2011;10:166 doi:10.1186/1475-2875-10-166 [Full text] (Added June 18, 2011) 32.Plasmodium knowlesi: Reservoir Hosts and Tracking the Emergence in Humans and Macaques. Lee K-S, Divis PCS, Zakaria SK, Matusop A, Julin RA, et al. PLoS Pathog 2011;7(4):e1002015. doi:10.1371/journal.ppat.1002015. [Full text] (Added Apr 11, 2011) 33.Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes. Audrey Sicard et al. Cellular Microbiology 4 March 2011. DOI: 10.1111/j.1462-5822.2011.01582.x [Full text] (Added Mar 10, 2011) 34.Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes. Weiguo Fang et al. Science 25 February 2011;331(6020):1074-1077 DOI: 10.1126/science.1199115 [Abstract | Podcast] (Added Feb 25, 2011) 35.malERA – a research agenda for malaria eradication on PLoS Medicine [PLoS Collections] (Added Jan 27, 2011) 36.Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte. Riglar DT et al. Cell Host & Microbe. 20 January 2011;9(1):9-20. Free Full text (Added Jan 21, 2011) 37.Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Arjen M Dondorp et al. The Lancet. Early online Publication, 8 November 2010 doi:10.1016/S0140-6736(10)61924-1. Free Full text (Added Nov 9, 2010) 38.Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Gretchen L Birbeck et al. The Lancet Neurology. Early online Publication, 4 November 2010. doi:10.1016/S1474-4422(10)70270-2 Abstract (Added Nov 9, 2010) 39. Malaria Elimination: Lancet Special, Oct 29, 2010 (Added Nov 3, 2010) 40.Widespread Divergence Between Incipient Anopheles gambiae Species Revealed by Whole Genome Sequences MKN Lawniczak, SJ Emrich, AK Holloway et al. Science. 22 October 2010;330(6003):512-514. Abstract (Added Oct 26, 2010) 41.The Armadillo Repeat Protein PF16 Is Essential for Flagellar Structure and Function in Plasmodium Male Gametes.Straschil U, Talman AM, Ferguson DJP, Bunting KA, Xu Z, et al.. PLoS onE. 2010;5(9): e12901. doi:10.1371/journal.pone.0012901. Free Full Text (Added Oct 26, 2010) 42.Adult and child malaria mortality in India: a nationally representative mortality survey Neeraj Dhingra, Prabhat Jha, Vinod P Sharma et al. The Lancet. 21 October 2010 doi:10.1016/S0140-6736(10)60831-8. Free Full Text (Added Oct 23, 2010) 43.India's invisible malaria burden. Simon I Hay, Peter W Gething, Robert W Snow. The Lancet. 21 October 2010 doi:10.1016/S0140-6736(10)61084-7 Free Full Text (Added Oct 23, 2010) 44.Chloroquine Clinical Failures in P. falciparum Malaria Are Associated with Mutant Pfmdr-1, Not Pfcrt in Madagascar. Andriantsoanirina V, Ratsimbasoa A, Bouchier C, et al. PLoS onE 5(10): e13281. doi:10.1371/journal.pone.0013281 Free Full Text (Added Oct 23, 2010) 45.Severe Imported Falciparum Malaria: A Cohort Study in 400 Critically Ill Adults. Bruneel F, Tubach F, Corne P, Megarbane B, Mira J-P, et al. PLoS onE 5(10): e13236. doi:10.1371/journal.pone.0013236 Free Full Text (Added Oct 23, 2010) 46.Distinct Olfactory Signaling Mechanisms in the Malaria Vector Mosquito Anopheles gambiae. Liu C, Pitts RJ, Bohbot JD, Jones PL, Wang G, et al. PLoS Biol 2010;8(8): e1000467. doi:10.1371/journal.pbio.1000467 Free Full Text (Added Sep 2, 2010) 47.Artemisinin resistant P. falciparum: Can the genie be put back in the bottle Egan TJ. Future Microbiol 2009;4(6)637-639 Free Full Text (Added Oct 14, 2009) 48.Proteome Analysis of Plasmodium falciparum Extracellular Secretory Antigens at Asexual Blood Stages Reveals a Cohort of Proteins with Possible Roles in Immune Modulation and Signaling. Meha Singh et al. Molecular & Cellular Proteomics 2009;8:2102-2118 Abstract (Added Oct 1, 2009) 49.Reliable enumeration of malaria parasites in thick blood films using digital image analysis John A Frean. Malaria Journal 2009, 8:218 doi:10.1186/1475-2875-8-218 Free Full Text (Added Sep 29, 2009) 50.Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial Matthew J Kirby et al. The Lancet September 2009;374(9694):998-1009 Free Full Text (Added Sep 29, 2009) 51.House screening for malaria control John E Gimniga, Laurence Slutsker. The Lancet September 2009;374(9694):954-955 Free Full Text (Added Sep 29, 2009) 52.Artemisinin Resistance in Plasmodium falciparum Malaria Arjen M. Dondorp et al. NEJM July 30, 2009;361(5):455-467 Free Full Text (Added Sep 28, 2009) 53.Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials John J Aponte et al. The Lancet Early online Publication, 17 September 2009doi:10.1016/S0140-6736(09)61258-7 Abstract (Added Sep 18, 2009) 54.Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite Ivo Mueller et al. Lancet Infect Dis September 2009;9(9):555-566 Abstract (Added Sep 17, 2009) 55.Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity Naresh Sunduru et al.Bioorganic & Medicinal Chemistry September 2009;17(17):6451-6462 Abstract (Added Sep 17, 2009) 56.Malaria severity status in patients with soil-transmitted helminth infections. Abraham Degarege et al. Acta Tropica October 2009;112(1):8-11 Abstract (Added Sep 17, 2009) 57.Mobile Phone Based Clinical Microscopy for Global Health Applications. Breslauer DN, Maamari RN, Switz NA, Lam WA, Fletcher DA. PLoS onE 2009;4(7): e6320. doi:10.1371/journal.pone.0006320 Free Full Text (Added Aug 27, 2009) 58.The origin of malignant malaria Stephen M. Rich et al. PNAS www.pnas.org/cgi/doi/10.1073pnas.0907740106 Free Full Text (Added Aug 7, 2009) 59.Can Prenatal Malaria Exposure Produce an Immune Tolerant Phenotype?: A Prospective Birth Cohort Study in Kenya Indu Malhotra et al. PLoS Med 2009;6(7): e1000116. doi:10.1371/journal.pmed.1000116, Article ID 415953 Free Full Text (Added Aug 5, 2009) 60.Unraveling the Impact of Malaria Exposure Before Birth Lars Hviid PLoS Med 2009;6(7): e1000117. Free Full Text (Added Aug 5, 2009) 61.Protection against a Malaria Challenge by Sporozoite Inoculation Meta Roestenberg et al. NEJM. 2009;361(5):468-477 Free Full Text (Added Aug 5, 2009) 62.Artemisinin Resistance in Plasmodium falciparum Malaria Arjen M. Dondorp et al. NEJM. 2009;361(5):455-467 Free Full Text (Added Aug 5, 2009) 63.Platelets, Pyrexia, and Plasmodia Doron C. Greenbaum, Garret A. FitzGerald NEJM. 2009;361(5):526-528 Abstract (Added Aug 5, 2009) 64.A monkey’s tale: The origin of Plasmodium vivax as a human malaria parasite Ananias A. Escalante et al. PNAS. 2005;102(6):1980-85 Free Full Text (Added Aug 5, 2009) 65.Rapid Diagnosis of Malaria Miguel A SanJoaquin, Clinton K.Murray, Jason W. Bennett Interdisciplinary Perspectives on Infectious Diseases. 2009, Article ID 415953, 7 pages doi:10.1155/2009/415953. Free Full Text (Added July 1, 2009) 66.Comparing Water, Bovine Milk, and Indoor Residual Spraying as Possible Sources of DDT and Pyrethroid Residues in Breast Milk Barbara Sereda, Henk Bouwman, Henrik Kylin ournal of Toxicology and Environmental Health. January 2009 Part A;72(14):897-908 Abstrat (Added July 1, 2009) 67.Malaria and vitamin A deficiency in African children: a vicious circle? Miguel A SanJoaquin, Malcolm E Molyneux Malaria Journal. 2009;8:134 doi:10.1186/1475-2875-8-134. Free Full Text (Added June 27, 2009) 68.The effect of mimicking febrile temperature and drug stress on malarial development Ratchaneewan Aunpad et al. Annals of Clinical Microbiology and Antimicrobials. 2009;8:19 doi:10.1186/1476-0711-8-19. Free Full Text (Added June 27, 2009) 69.Risk factors for malaria deaths in Jalpaiguri district, West Bengal, India: evidence for further action Jagannath Sarkar et al. Malaria Journal. 2009;8:133 doi:10.1186/1475-2875-8-133. Free Full Text (Added June 18, 2009) 70.Malaria Diagnosis: A Brief Review Noppadon Tangpukdee, Chatnapa Duangdee, Polrat Wilairatana, Srivicha Krudsood Korean J Parasitol. 2009 Jun;47(2):93-102. Free Full Text (Added June 16, 2009) 71.Malarial Hepatopathy in Falciparum Malaria Shahnaz Shah, Liaquat Ali, Rukhsana Abdul Sattar, Tariq Aziz, Tahir Ansari, Jamal Ara Journal of the College of Physicians and Surgeons Pakistan. 2009;19;(6):367-370. Free Full Text (Added June 16, 2009) 72.Simulation of the cost-effectiveness of malaria vaccines Fabrizio Tediosi et al. Malaria Journal. 2009;8:127 doi:10.1186/1475-2875-8-127 Free Full Text (Added June 16, 2009) 73.Larvicidal activity of neem oil (Azadirachta indica) formulation against mosquitoes Virendra K Dua et al. Malaria Journal. 2009;8:124 doi:10.1186/1475-2875-8-124 Free Full Text (Added June 16, 2009) 74.Good News in Malaria Control… Now What? Richard W. Steketee. Am. J. Trop. Med. Hyg. 2009;80(6):879–880. Free Full Text (Added June 9, 2009) 75.Severe Retinal Whitening in an Adult with Cerebral Malaria. Maude RJ, Hassan MU, Beare NAV. Am. J. Trop. Med. Hyg. 2009;80(6):881. Free Full Text (Added June 9, 2009) 76.Comparison of Sulfadoxine-Pyrimethamine, Unsupervised Artemether-Lumefantrine, and Unsupervised Artesunate-Amodiaquine Fixed-Dose Formulation for Uncomplicated Plasmodium falciparum Malaria in Benin: A Randomized Effectiveness Noninferiority Trial. Jean-Franc et al. The Journal of Infectious Diseases 2009; 200:57–65. Abstract (Added June 9, 2009) 77.Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Rowe JA, Claessens A, Corrigan RA, Arman M. Expert reviews in molecular medicine May 2009; Vol. 11:e16. doi:10.1017/S1462399409001082. Abstract (Added June 9, 2009) 78.Effect of Malaria Rapid Diagnostic Tests on the Management of Uncomplicated Malaria with Artemether-Lumefantrine in Kenya: A Cluster Randomized Trial. Jacek Skarbinski et al. Am. J. Trop. Med. Hyg. 2009;80(6):919-926. Abstract (Added June 9, 2009) 79.Vivax Malaria: A Major Cause of Morbidity in Early Infancy. Jeanne R. Poespoprodjo et al. Clinical Infectious Diseases 2009;48:1704–1712. Abstract (Added June 9, 2009) 80.A New Malaria Agent in African Hominids. Ollomo B, Durand P, Prugnolle F, Douzery E, Arnathau C, et al. PLoS Pathog 2009;5(5): e1000446. doi:10.1371/journal.ppat.1000446. Free Full Text (Added June 3, 2009) 81.Antimalarial natural products of marine and freshwater origin Karl Gademann, Joanna Kobylinska. The Chemical RecordMay 2009. Abstract (Added June 3, 2009) 82.Malaria Control Insecticide Residues in Breastmilk: The Need to Consider Infant Health Risks Hindrik Bouwman, Henrik Kylin Env Health PerspMay 2009. Free Full Text (Added June 3, 2009) 83.Strong Gametocytocidal Effect of Methylene Blue-Based Combination Therapy against Falciparum Malaria: A Randomised Controlled Trial. Coulibaly B, Zoungrana A, Mockenhaupt FP, Schirmer RH, Klose C, et al. PLoS onE2009;4(5): e5318. doi:10.1371/journal.pone.0005318. Free Full Text (Added June 3, 2009) 84.Influence of Rapid Malaria Diagnostic Tests on Treatment and Health Outcome in Fever Patients, Zanzibar—A Crossover Validation Study Msellem MI, Mårtensson A, Rotllant G, Bhattarai A, Strömberg J, et al. PLoS Med2009;6(4): e1000070. Free Full Text (Added May 5, 2009) 85.The Role of Rapid Diagnostic Tests in Managing Malaria. Bisoffi Z, Gobbi F, Angheben A, Van den Ende J. PLoS Med. 2009;6(4): e1000063 Free Full Text (Added May 5, 2009) 86.Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A. Spring MD, Cummings JF, Ockenhouse CF, Dutta S, Reidler R, et al. PLoS onE 2009;4(4):e5254 Free Full Text (Added May 5, 2009) 87.Towards high-throughput molecular detection of Plasmodium: new approaches and molecular markers Steenkeste N, Incardona S, Chy S et al. Malaria Journal2009;8:86. Free Full Text (Added May 5, 2009) 88.The Malaria Severity Score: a Method for Severity Assessment and Risk Prediction of Hospital Mortality for Falciparum Malaria in Adults MK Mohapatra, SP Das. JAPI. 2009;57:119-126 Free Full Text (Added Feb 10, 2009) 89.Malarial anemia and STAT6 Robson KJH, Weatherall DJ. Haematologica. 2009;94(2) Free Full Text (Added Feb 10, 2009) 90.STAT6-mediated suppression of erythropoiesis in an experimental model of malarial anemia Thawani N, Tam M, Stevenson MM. Haematologica. 2009;94(2):195-204 Free Full Text (Added Feb 10, 2009) 91.Probability of emergence of antimalarial resistance in different stages of the parasite life cycle Wirichada Pongtavornpinyo et al. Journal compilation. 2009;52–61 Free Full Text (Added Feb 10, 2009) 92.Malarial Retinopathy in Cerebral Malaria Beare NAV, Glover SJ, Molyneux M. Am. J. Trop. Med. Hyg. 2009;80(2):171 Free Full Text (Added Feb 10, 2009) 93.Methemoglobinemia and Adverse Events in Plasmodium vivax Malaria Patients Associated with High Doses of Primaquine Treatment Jaime Carmona-Fonseca, Gonzalo Álvarez, Amanda Maestre. Am. J. Trop. Med. Hyg. 2009;80(2):188-193 Abstract (Added Feb 10, 2008) 94.Severe Plasmodium vivax Malaria: A Report on Serial Cases from Bikaner in Northwestern India Kochar DK et al. Am. J. Trop. Med. Hyg. 2009;80(2):194-198 Abstract (Added Feb 10, 2009) 95.Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review PrayGod G, De Frey A, Eisenhut M. Malaria Journal. 2008, 7:210 Free Full Text (Added Oct 28, 2008) 96.Comparative genomics of the neglected human malaria parasite Plasmodium vivax Carlton JM et al. Nature. 455, 757-763 (9 October 2008) Free Full Text (Added Oct 24, 2008) 97.Malaria research in the post-genomic era Winzeler EA. Nature. 455, 751-756 (9 October 2008) Abstract (Added Oct 24, 2008) 98.Burden of Cerebral Malaria in Central India (2004–2007) Jain V et al. Am. J. Trop. Med. Hyg. 2008;79(4):636-642 Abstract (Added Oct 24, 2008) 99.Biological control of mosquito populations through frogs: Opportunities & constrains Raghavendra K, Sharma P, Dash AP. Indian J Med Res . 2008;128:22-25 Free Full Text (Added Oct 8, 2008) 100.Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: A report from three study sites in sub-Saharan Africa Ajayi IO et al. Malaria Journal. 2008, 7:190(37) Free Full Text (Added Oct 8, 2008) 101.Neurosyphilis, Malaria, and the Discovery of Antipsychotic Agents Frankenburg FR, Baldessarini RJ. Harvard Review of Psychiatry. 2008;16(5):299-307(37) Abstract (Added Oct 8, 2008) 102.Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum. Park Y, Diez-Silva M, Popescu G et al. PNAS. 2008;105(37) Free Full Text (Added Sep 10, 2008) 103.Platelet Factor 4 Mediates Inflammation in Experimental Cerebral Malaria. Srivastava K, Cockburn IA, Swaim A et al. Cell Host & Microbe. 2008;4(2):179-187 Abstract (Added Aug 21, 2008) 104.Presumptive treatment of fever cases as malaria: Help or hindrance for malaria control? Roly D Gosling, Christopher J Drakeley, Alex Mwita, Daniel Chandramohan. Malaria Journal. 2008, 7:132 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-132.pdf (Added Jul 28, 2008) 105.The usefulness of a new rapid diagnostic test, the First Response® Malaria Combo (pLDH/HRP2) card test, for malaria diagnosis in the forested belt of central India Praveen K Bharti, Nipun Silawat, Pushpendra P Singh, Mrigendra P Singh1, Manmohan Shukla, Gyan Chand, Aditya P Dash, Neeru Singh. Malaria Journal. 2008, 7:126 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-126.pdf (Added Jul 28, 2008) 106.Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. Lucy C Okell1, Chris J Drakeley, Azra C Ghani, Teun Bousema, Colin J Sutherland. Malaria Journal. 2008, 7:125 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-125.pdf (Added Jul 28, 2008) 107.Plasmodium falciparum in ancient Egypt. [letter]. Nerlich AG, Schraut B, Dittrich S, Jelinek T, Zink AR. Emerg Infect Dis [serial on the Internet]. 2008 Aug Full Text at http://www.cdc.gov/EID/content/14/8/1317.htm (Added Jul 28, 2008) 108.Cerebral Malaria in Children Is Associated With Long-term Cognitive Impairment. John CC, MD, Bangirana P, Byarugaba J et al. PEDIATRICS. Vol. 122 No. 1 July 2008, pp. e92-e99 Full Text at http://pediatrics.aappublications.org/cgi/content/full/122/1/e92 (Added Jul 14, 2008) 109.Evaluation of light microscopy and rapid diagnostic test for the detection of malaria under operational field conditions: a household survey in Ethiopia. Endeshaw T, Gebre T, Ngondi J et al. Malaria Journal. 2008;7:118 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-118.pdf (Added Jul 14, 2008) 110.First Case of Emergence of Atovaquone-Proguanil (MalaroneTM) Resistance in Plasmodium falciparum During Treatment in Traveller from Comoros. Savini H, Bogreau H, Bertaux L et al. Antimicrob. Agents Chemother. doi:10.1128/AAC.00282-08 Abstract at http://aac.asm.org/cgi/content/abstract/AAC.00282-08v1 (Added Apr 29, 2008) 111.Qinghaosu (Artemisinin): The Price of Success White NJ. Science 2008;320(5874):330-334 Abstract at http://www.sciencemag.org/cgi/content/abstract/320/5874/330 (Added Apr 29, 2008) 112.A Malaria Fingerprint in the Human Genome? Daily JP, Sabeti P. NEJM Apr 16, 2008 Full text at http://content.nejm.org/cgi/content/full/NEJMe0801414 (Added Apr 22, 2008) 113.A magneto-optic route towards the in-vivo diagnosis of malaria: preliminary results and pre-clinical trial data Newman DM, Heptinstall J, Matelon RJ et al. Biophys J Apr 2008. Full text at http://www.biophysj.org/cgi/rapidpdf/biophysj.107.128140v1 (Added Apr 22, 2008) 114.Adverse Pregnancy Outcomes in an Area Where Multidrug-Resistant Plasmodium vivax and Plasmodium falciparum Infections Are Endemic Poespoprodjo JR, Fobia W,Kenangalem E et al. Clinical Infectious Diseases 2008;46:1374–1381 Abstract at http://www.journals.uchicago.edu/doi/abs/10.1086/586743 (Added Apr 22, 2008) 115.Dihydroartemisinin—Piperaquine Rescue Treatment of Multidrug-resistant Plasmodium falciparum Malaria in Pregnancy: A Preliminary Report Rijken MJ, McGready R, Boel ME et al. Am. J. Trop. Med. Hyg. 2008;78(4):543-545 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/4/543 (Added Apr 22, 2008) 116.Malaria: progress, perils, and prospects for eradication Greenwood BM, Fidock DA, Kyle DE et al. J. Clin. Invest. 2008;118(4):1266-1276 Full Text at http://www.jci.org/articles/view/33996 (Added Apr 22, 2008) 117.Malaria Vector Management: Where Have We Come From and Where Are We Headed? Muturi EJ, Burgess P, Novak RJ. Am. J. Trop. Med. Hyg. 2008;78(4):536–537. Full Text at http://www.ajtmh.org/cgi/reprint/78/4/536 (Added Apr 22, 2008) 118.Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda. Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon, Chi Phan. Malaria Journal 2008;7:49 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-49.pdf 119.Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues Andrews KT, Tran TN, Lucke AJ et al. Antimicrobial Agents and Chemotherapy. 2008;52(4):1454-1461. Abstract at http://aac.asm.org/cgi/content/abstract/52/4/1454 120.Inhibition of Efflux of Quinolines as New Therapeutic Strategy in Malaria Maud H, Sandrine A, Christophe R, Jacques B, Bruno P. Current Topics in Medicinal Chemistry. 2008;8(7):563-578(16) Abstract at http://www.ingentaconnect.com/content/ben/ctmc/2008/00000008/00000007/art00003 121.Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies. Melba Gomes, Isabela Ribeiro1, Marian Warsame, Harin Karunajeewa, Max Petzold. BMC Infectious Diseases 2008;8:39 Full Text available at http://www.biomedcentral.com/content/pdf/1471-2334-8-39.pdf 122.Plasmodium-Induced Inflammation by Uric Acid. Orengo JM, Evans JE, Bettiol E, Leliwa-Sytek A, Day K, et al. PLoS Pathog 2008;4(3): e1000013. doi:10.1371/journal.ppat.1000013 Full Text available at http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1000013 123.The Alpha-Carbonic Anhydrase from the Malaria Parasite and its Inhibition. Jerapan K, Supuran CT. Current Pharmaceutical Design. 2008;14(7):631-640. Abstract available at http://www.ingentaconnect.com/content/ben/cpd/2008/00000014/00000007/art00005 124.Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda. Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon, Chi Phan. Malaria Journal 2008;7:49 doi:10.1186/1475-2875-7-49. Full Text Available at http://www.malariajournal.com/content/pdf/1475-2875-7-49.pdf 125.Increased Plasmodium falciparum Gametocyte Production in Mixed Infections with P. malariae. J. Teun Bousema, Chris J. Drakeley, Petra F. Mens, Theo Arens, Rein Houben, Sabah A. Omar, Louis C. Gouagna, Henk Schallig, Robert W. Sauerwein. Am. J. Trop. Med. Hyg. 2008;78(3):442-448 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/442?etoc 126.Malaria in Pregnancy in the Solomon Islands: Barriers to Prevention and Control. Bridget Appleyard, Makiva Tuni, Qin Cheng, Nanhua Chen, Joan Bryan, James S. McCarthy. Am. J. Trop. Med. Hyg. 2008;78(3):449-454 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/449?etoc 127.Geographical Distribution of Amino Acid Mutations in Plasmodium vivax DHFR and DHPS from Malaria Endemic Areas of Thailand. Kanchana Rungsihirunrat, Carol Hopkins Sibley, Mathirut Mungthin, Kesara Na-Bangchang. Am. J. Trop. Med. Hyg. 2008;78(3):462-467 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/462?etoc
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