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Cập nhật các ấn phẩm nghiên cứu về sốt rét và các bệnh ký sinh trùng trên toàn cầu

5 năm trở lại đây, nhiều công trình nghiên cứu quy mô lớn được tiến hành nhằm giải quyết các mục tiêu của Chiến lược Phòng chống và loại trừ sốt rét trên toàn cầu, đặc biệt tại Đông Nam Á và châu Phi được đăng tải trên các tạp chí y sinh học nổi tiếng thế giới như PLOS o­ne, Nature, PNAS, The Lancet, Malaria Journal, Acta Tropica, Parasites & Vectors, Cell Host & Microbe, PEDIATRICS, Journal of Infection and Public Health, New England Journal of Medicine...

Sốt rét vẫn còn là một vấn đề y tế công cộng đối với nhân loại. Nó đã gây ra số tử vong hơn cả chiến tranh, ảnh hưởng đến lịch sử và phân bố địa lý cũng như sự tiến bộ của nhân loại, đồng thời làm thay đổi nhiều gen của chúng ta. Trên toàn cầu, ước tính có 3.2 tỷ người có nguy cơ mắc sốt rét, 1.2 tỷ người có nguy cơ cao. Theo báo cáo sốt rét toàn cầu năm 2015, sốt rét đã gây nên 214 triệu ca nhiễm và 438.000 ca tử vong, gần 90% số ca tử vong này xảy ra ở châu Phi, 70% trong số đó rơi vào trẻ em dưới 5 tuổi. Tuy nhiên, các ngân sách cho sốt rét toàn cầu cần phải tăng nữa, loài P. falciparum đã kháng với hầu hết các thuốc sốt rét dọc theo khu vực biên giới Campuchia-Thái Lan và 78 quốc gia có báo cáo các loại số liệu giám sát từ năm 2010, 60 báo cáo kháng với ít nhất 1 loại hóa chất diệt côn trùng trong lĩnh vực phòng chống vector từ các điểm nghiên cứu theo dõi và 49 quốc gia báo cáo kháng với hai hay nhiều nhóm hóa chất diệt côn trùng. Mặc dù, có rất nhiều nổ lực vè ngân quỹ và nguồn lực khác đầu tư để đạt được mục tiêu thiên niên kỷ, song các thách thức liên quan đến sốt rét vẫn còn tiếp tục.

 

Fluorescence In Situ Hybridization (FISH) Assays for Diagnosing Malaria in Endemic Areas.Jyotsna Shah, Olivia Mark, Helena Weltman, Nicolas Barcelo, Wai Lo, Danuta Wronska, Srinivas Kakkilaya, Aravinda Rao, Shalia T. Bhat, Ruchi Sinha, Sabah Omar, Peter O’bare, Manuel Moro, Robert H. Gilman, Nick Harris. PLOS o­ne. September 2, 2015. DOI: 10.1371/journal.pone.0136726. Full Text at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136726 [Added: Sep 7, 2015]

A novel multiple-stage antimalarial agent that inhibits protein synthesis.Baragaña B et al. Nature. 18 June 2015;522:315–320. doi:10.1038/nature14451 [Abstract] (Added: Jun 18, 2015)

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria. Goel S et al. Nature Medicine. 2015. doi:10.1038/nm.3812. [Abstract] (Added Mar 12, 2015)

Antimalarial drug discovery — approaches and progress towards new medicines. Flannery EL, Chatterjee AK, Winzeler EA. Nature Reviews Microbiology. 2013;11:849–862. doi:10.1038/nrmicro3138.[Abstract] (Added Jan 9, 2014)

Blocking malaria transmission to Anopheles mosquitoes using artemisinin derivatives and primaquine: a systematic review and meta-analysis. Abay SM. Parasites & Vectors 2013;6:278.[Full Text] (Added Nov 5, 2013)

The complexity of medicinal plants: The traditional Artemisia annua formulation, current status and future perspectives. van der Kooy F, Sullivan SE. Journal of Ethnopharmacology. 28 October 2013;150(1):1–13.[Abstract] (Added Nov 5, 2013)

The activation of vivax malaria hypnozoites by infectious diseases. Shanks GD, White NJ. The Lancet Infectious Diseases.October 2013;13(10):900-906. doi:10.1016/S1473-3099(13):70095-1. [Full Text] (Added Nov 5, 2013)

Dried Whole Plant Artemisia annua as an Antimalarial Therapy. Elfawal MA, Towler MJ, Reich NG, Golenbock D, Weathers PJ, et al. PLoS o­nE. 2012;7(12):e52746. doi:10.1371/journal.pone.0052746[Full Text] (Added Feb 7, 2013)

Evidence and Implications of Mortality Associated with Acute Plasmodium vivax Malaria. J. Kevin Baird. Clin. Microbiol. Rev. January 2013;26(1):36-57. doi: 10.1128/?CMR.00074-12[Abstract] (Added Feb 7, 2013)

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region.Abdulla S, Salim N, Tanner M et al. Malaria Journal. 2013;12:11.[Full Text] (Added Feb 7, 2013)

Red blood cell membrane dynamics during malaria parasite egress. Callan-Jones A et al.Biophys J. 2012 Dec 19;103(12):2475-83. doi: 10.1016/j.bpj.2012.11.008. Epub 2012 Dec 18.[Abstract] (Added Feb 7, 2013)

Assessment of the Molecular Marker of Plasmodium falciparum Chloroquine Resistance ( Pfcrt) in Senegal after Several Years of Chloroquine Withdrawal.Ndiaye M et al. Am J Trop Med Hyg. August 27, 2012, doi: 10.4269/ajtmh.2012.11-0709.[Full Text] (Added Oct 4, 2012)

Malaria Control and Elimination in Sri Lanka: Documenting Progress and Success Factors in a Conflict Setting. Abeyasinghe RR, Galappaththy GNL, Smith Gueye C, Kahn JG, Feachem RGA. PLoS o­nE. 2012;7(8): e43162. doi:10.1371/journal.pone.0043162.[Full Text] (Added Sep 7, 2012)

Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study. Rosanas-Urgell A, Lin E, Manning L, Rarau P, Laman M, et al. PLoS Med. 2012;9(9):e1001305. doi:10.1371/journal.pmed.1001305.[Full Text] (Added Sep 6, 2012)

High levels of DDT in breast milk: Intake, risk, lactation duration, and involvement of gender. Hindrik Bouwmana, Henrik Kylinb, Barbara Seredad, Riana Bornman. Env Pollu. November 2012;170:63–70.[Abstract] (Added Sep 6, 2012)

Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance. LaMonte G et al. Cell Host & Microbe. 16 August 2012;12(2):187–199.[Abstract] (Added Aug 30, 2012)

New global estimates of malaria deaths White NJ et al. The Lancet. 2012;380(9841):559- 560.[Correspondence] (Added Aug 14, 2012)

Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity Chan J et al. J Clin Invest. 2012. doi:10.1172/JCI62182.[Full Text] (Added Aug 14, 2012)

The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Neafsey DE et al. Nature Genetics 2012. doi:10.1038/ng.2373[Letter] (Added Aug 14, 2012)

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing Manske M et al. Nature. 2012. doi:10.1038/nature11174.[Letter] (Added Jun 30, 2012)

Relapse of imported Plasmodium vivax malaria is related to primaquine dose: a retrospective study Townell N et al. Malaria Journal. 2012;11:214 doi:10.1186/1475-2875-11-214.[Full Text] (Added Jun 30, 2012)

New targets, new hope: novel drug targets for curbing malaria.Arora N, Banerjee AK. Mini Rev Med Chem. 2012 Mar;12(3):210-26.[Abstract] (Added Jun 30, 2012)

Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa Nayyar GML, Breman JG,Newton PN, Herrington J. The Lancet Infectious Diseases. June 2012;12(6)488-496.[Full Text] (Added Jun 2, 2012)

Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis Taylor SM, Parobek CM, Fairhurst RM. The Lancet Infectious Diseases. June 2012;12(6):457-468. [Full Text] (Added Jun 2, 2012)

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections Pillai DR et al. Malaria Journal 2012;11:131. [Full Text] (Added Apr 28, 2012)

Plasmodium vivax malaria–associated acute kidney injury, India, 2010–2011. Kute VB, Trivedi HL, Vanikar AV, Shah PR, Gumber MR, Patel HV, et al. Emerg Infect Dis. May 2012.[Full Text] (Added Apr 28, 2012)

Plasmodium vivax Adherence to Placental Glycosaminoglycans. Chotivanich K, Udomsangpetch R, Suwanarusk R, Pukrittayakamee S, Wilairatana P, et al. PLoS o­nE. 2012;7(4):e34509.[Full Text] (Added Apr 28, 2012)

The anaemia of Plasmodium vivax malaria. Douglas NM et al. Malaria Journal 2012;11:135.[Full Text] (Added Apr 28, 2012)

Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission. Huho BJ et al. Malaria Journal. 2012;11:118.[Full Text] (Added Apr 28, 2012)

Malaria resurgence: a systematic review and assessment of its causes. Cohen JM et al. Malaria Journal 2012;11:122.[Full Text] (Added Apr 26, 2012)

Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites.Ghumra A, Semblat J-P, Ataide R, Kifude C, Adams Y, et al. PLoS Pathog. 2012;8(4):e1002665. doi:10.1371/journal.ppat.1002665 [Full Text] (Added Apr 22, 2012)

Toward fast malaria detection by secondary speckle sensing microscopy. Dan Cojoc, Sara Finaurini, Pavel Livshits, Eran Gur, Alon Shapira, Vicente Mico, and Zeev Zalevsky. Biomedical Optics Express. 2012;3(5):991-1005. [Full Text] (Added Apr 22, 2012)

A global map of dominant malaria vectors. Sinka ME et al. Parasites & Vectors. 2012;5:69. doi:10.1186/1756-3305-5-69 [Full Text] (Added Apr 14, 2012)

Emergence of artemisinin-resistant malaria o­n the western border of Thailand: a longitudinal study. Phyo AP et al. The Lancet. 5 April 2012. doi:10.1016/S0140-6736(12)60484-X. [Full Text] (Added Apr 9, 2012)

A Major Genome Region Underlying Artemisinin Resistance in Malaria. Cheeseman IH et al. Science. 6 April 2012;336(6077):79-82. DOI: 10.1126/science.1215966. [Abstract] (Added Apr 9, 2012)

Emergence of artemisinin-resistant malaria o­n the western border of Thailand: a longitudinal study. Phyo AP et al. The Lancet. 5 April 2012. doi:10.1016/S0140-6736(12)60484-X. [Full Text] (Added Apr 9, 2012)

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum. Augagneur Y et al. PNAS. April 2, 2012. doi: 10.1073/pnas.1203516109 [Abstract] (Added Apr 4, 2012)

Risk factors for mortality from imported falciparum malaria in the United Kingdom over 20 years: an observational study. Checkley AM et al. BMJ 2012;344. doi: 10.1136/bmj.e2116[Full Text] | Elderly are almost 10 times more likely to die of malaria than younger tourists BMJ Press Release. Mar 27, 2012[Full Text] (Added Apr 1, 2012)

Global malaria mortality between 1980 and 2010: a systematic analysis Murray CJL et al. The Lancet. 4 February 2012;379(9814):413-431. doi:10.1016/S0140-6736(12)60034-8 [Full Text] | New estimates of malaria deaths: concern and opportunity The Lancet Editorial. 4 February 2012;379(9814):385. doi:10.1016/S0140-6736(12)60169-X [Full Text] (Added Feb 3, 2012)

Evaluation of the antiplasmodial and cytotoxicity potentials of husk fiber extracts from Cocos nucifera, a medicinal plant used in Nigeria to treat human malaria Adebayo JO, Santana AEG, Krettli AU. Hum Exp Toxicol. January 12, 2012 0960327111424298 doi: 10.1177/0960327111424298 [Abstract] (Added Feb 3, 2012)

A new world malaria map: Plasmodium falciparum endemicity in 2010. Gething PW et al. Malaria Journal 2011;10:378 doi:10.1186/1475-2875-10-378 [Abstract] (Added Jan 25, 2012)

Endoplasmic Reticulum PI(3)P Lipid Binding Targets Malaria Proteins to the Host Cell.Souvik Bhattacharjee, Robert V. Stahelin, Kaye D. Speicher, David W. Speicher, Kasturi Haldar. Cell. 20 January 2012;148(1):201-212. [Abstract] (Added Jan 22, 2012)

Structure of a Potential Antimalarial Drug Target Revealed?: Structure and Reaction Mechanism of Phosphoethanolamine Methyltransferase from Malaria Parasite Plasmodium falciparum. Antiparasitic Drug Target. J. Biol. Chem. 2012;287:1435. [Full Text] (Added Jan 21, 2012)

Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic review and meta-analysis.Obonyo CO, Juma EA. Malaria Journal 2012;11:2. doi:10.1186/1475-2875-11-2 [Full Text] (Added Jan 21, 2012)

The Use of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax Malaria. Bassat Q. PLoS Negl Trop Dis. 2011;5(12):e1325. doi:10.1371/journal.pntd.0001325[Full Text](Added Jan 21, 2012)

Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study McGready R et al. The Lancet Infectious Diseases. doi:10.1016/S1473-3099(11)70339-5. [Full Text] (Added Dec 14, 2011)

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice Wykes MN et al. PNAS June 20, 2011 [Abstract] (Added Dec 14, 2011)

Plasmodium falciparum Parasites are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model. Cassera MB, Hazleton KZ, Merino EF, Obaldia N III, Ho M-C, et al. PLoS o­nE 2011;6(11):e26916. doi:10.1371/journal.pone.0026916 [Full text] (Added Dec 14, 2011)

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum. Crosnier C et al. Nature 2011. doi:10.1038/nature10606 [Abstract] (Added Nov 11, 2011)

Effects of Artesunate o­n Parasite Recrudescence and Dormancy in the Rodent Malaria Model Plasmodium vinckei.LaCrue AN, Scheel M, Kennedy K, Kumar N, Kyle DE. PLoS o­nE 2011;6(10):e26689. doi:10.1371/journal.pone.0026689 [Full Text] (Added Oct 27, 2011)

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children. The RTS,S Clinical Trials Partnership. New England Journal of Medicine Oct 18, 2011[Full Text] (Added Oct 27, 2011)

Vaccine Platforms Combining Circumsporozoite Protein and Potent Immune Modulators, rEA or EAT-2, Paradoxically Result in Opposing Immune Responses. Schuldt NJ, Aldhamen YA, Appledorn DM, Seregin SS, Kousa Y, et al. PLoS o­nE 2011;6(8):e24147. doi:10.1371/journal.pone.0024147 [Full Text] (Added Oct 27, 2011)

Laboratory demonstration of a prozone-like effect in HRP2-detecting malaria rapid diagnostic tests: implications for clinical management Jennifer Luchavez et al. Malaria Journal 2011;10:286 doi:10.1186/1475-2875-10-286 [Full Text] (Added Oct 9, 2011)

Dramatic Decrease in Malaria Transmission after Large-Scale Indoor Residual Spraying with Bendiocarb in Benin, an Area of High Resistance of Anopheles gambiae to Pyrethroids Martin Akogbeto et al. Am J Trop Med Hyg 2011;85(4):86-593. doi: 10.4269/ajtmh.2011.10-0668 [Abstract] (Added Oct 9, 2011)

Net Benefits: A Multicountry Analysis of Observational Data Examining Associations between Insecticide-Treated Mosquito Nets and Health Outcomes.Lim SS, Fullman N, Stokes A, Ravishankar N, Masiye F, et al. PLoS Med 2011; 8(9):e1001091. doi:10.1371/journal.pmed.1001091. [Full Text] (Added Sep 17, 2011)

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum.Yeh E, DeRisi JL. PLoS Biol 2011;9(8): e1001138. doi:10.1371/journal.pbio.1001138 [Full Text] (Added Sep 5, 2011)

Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study. Trape JF et al.The Lancet Infectious Diseases. 18 August 2011. doi:10.1016/S1473-3099(11)70194-3 [Full Text] (Added Aug 22, 2011)


Rerooting the evolutionary tree of malaria parasites.
Outlaw DC, Ricklefs RE.  PNAS August 9, 2011;108(32):13183-13187. doi: 10.1073/pnas.1109153108 [Abstract] (Added Aug 12, 2011)

Resolving the phylogeny of malaria parasites.Rich SM, Xu G. PNAS August 9, 2011;108(32):12973-12974. doi: 10.1073/pnas.1110141108 [Abstract] (Added Aug 12, 2011)

Ivermectin Mass Drug Administration to Humans Disrupts Malaria Parasite Transmission in Senegalese Villages Kobylinski KC et al. Am J Trop Med Hyg 2011;85(1):3-5 [Abstract] (Added July 10, 2011)

Efficacy of Aquatain, a Monomolecular Film, for the Control of Malaria Vectors in Rice Paddies.Githeko AK, Koenraadt CJM. PLoS o­nE 2011;6(6):e21713. doi:10.1371/journal.pone.0021713 [Full text] (Added July 3, 2011)

Consequences of HIV infection o­n malaria and therapeutic implications: A systematic review. Clara Flateau, Guillaume Le Loup, Gilles Pialoux. The Lancet Infectious Diseases July 2011;11(7):541-556 [Full text] (Added June 25, 2011)

Plasmodium vivax malaria: Is it actually benign? Harpal Singh, Ankit Parakha, Srikanta Basua, Bimbadarh Ratha. Journal of Infection and Public Health June 2011;4(2):91-95[Abstract] (Added June 18, 2011)

Safety, pharmacokinetics and efficacy of artemisinins in pregnancy Veronica Ades. Infectious Disease Reports 2011;3(1)37-43 [Full text] (Added June 18, 2011)

Prozone in malaria rapid diagnostics tests: how many cases are missed? Philippe Gillet et al. Malaria Journal 2011;10:166 doi:10.1186/1475-2875-10-166 [Full text] (Added June 18, 2011)

Plasmodium knowlesi: Reservoir Hosts and Tracking the Emergence in Humans and Macaques. Lee K-S, Divis PCS, Zakaria SK, Matusop A, Julin RA, et al. PLoS Pathog 2011;7(4):e1002015. doi:10.1371/journal.ppat.1002015. [Full text] (Added Apr 11, 2011)

Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes.Audrey Sicard et al. Cellular Microbiology 4 March 2011. DOI: 10.1111/j.1462-5822.2011.01582.x [Full text] (Added Mar 10, 2011)

Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes. Weiguo Fang et al. Science 25 February 2011;331(6020):1074-1077 DOI: 10.1126/science.1199115 [AbstractPodcast] (Added Feb 25, 2011)

malERA – a research agenda for malaria eradication o­n PLoS Medicine [PLoS Collections] (Added Jan 27, 2011)

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte.Riglar DT et al. Cell Host & Microbe. 20 January 2011;9(1):9-20. Free Full text (Added Jan 21, 2011)

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Arjen M Dondorp et al. The Lancet. Early o­nline Publication, 8 November 2010 doi:10.1016/S0140-6736(10)61924-1. Free Full text (Added Nov 9, 2010)

Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Gretchen L Birbeck et al. The Lancet Neurology. Early o­nline Publication, 4 November 2010. doi:10.1016/S1474-4422(10)70270-2. Abstract (Added Nov 9, 2010)

Malaria Elimination: Lancet Special, Oct 29, 2010 (Added Nov 3, 2010)

Widespread Divergence Between Incipient Anopheles gambiae Species Revealed by Whole Genome Sequences MKN Lawniczak, SJ Emrich, AK Holloway et al. Science. 22 October 2010;330(6003):512-514. Abstract (Added Oct 26, 2010)

The Armadillo Repeat Protein PF16 Is Essential for Flagellar Structure and Function in Plasmodium Male Gametes.Straschil U, Talman AM, Ferguson DJP, Bunting KA, Xu Z, et al. PLoS o­nE. 2010;5(9): e12901. doi:10.1371/journal.pone.0012901. Free Full Text (Added Oct 26, 2010)

Adult and child malaria mortality in India: a nationally representative mortality survey Neeraj Dhingra, Prabhat Jha, Vinod P Sharma et al. The Lancet. 21 October 2010 doi:10.1016/S0140-6736(10)60831-8. Free Full Text (Added Oct 23, 2010)

India’s invisible malaria burden. Simon I Hay, Peter W Gething, Robert W Snow. The Lancet. 21 October 2010 doi:10.1016/S0140-6736(10)61084-7 Free Full Text (Added Oct 23, 2010)

Chloroquine Clinical Failures in P. falciparum Malaria Are Associated with Mutant Pfmdr-1, Not Pfcrt in Madagascar. Andriantsoanirina V, Ratsimbasoa A, Bouchier C, et al. PLoS o­nE 5(10): e13281. doi:10.1371/journal.pone.0013281 Free Full Text (Added Oct 23, 2010)

Severe Imported Falciparum Malaria: A Cohort Study in 400 Critically Ill Adults. Bruneel F, Tubach F, Corne P, Megarbane B, Mira J-P, et al. PLoS o­nE 5(10): e13236. doi:10.1371/journal.pone.0013236 Free Full Text (Added Oct 23, 2010)

Distinct Olfactory Signaling Mechanisms in the Malaria Vector Mosquito Anopheles gambiae. Liu C, Pitts RJ, Bohbot JD, Jones PL, Wang G, et al. PLoS Biol 2010;8(8): e1000467. doi:10.1371/journal.pbio.1000467 Free Full Text (Added Sep 2, 2010)

Artemisinin resistant P. falciparum: Can the genie be put back in the bottle Egan TJ. Future Microbiol 2009;4(6)637-639 Free Full Text (Added Oct 14, 2009)

Proteome Analysis of Plasmodium falciparum Extracellular Secretory Antigens at Asexual Blood Stages Reveals a Cohort of Proteins with Possible Roles in Immune Modulation and Signaling. Meha Singh et al. Molecular & Cellular Proteomics 2009;8:2102-2118 Abstract (Added Oct 1, 2009)

Reliable enumeration of malaria parasites in thick blood films using digital image analysis John A Frean. Malaria Journal 2009, 8:218 doi:10.1186/1475-2875-8-218 Free Full Text (Added Sep 29, 2009)

Effect of two different house screening interventions o­n exposure to malaria vectors and o­n anaemia in children in The Gambia: a randomised controlled trial Matthew J Kirby et al. The Lancet September 2009;374(9694):998-1009 Free Full Text (Added Sep 29, 2009)

House screening for malaria control John E Gimniga, Laurence Slutsker. The Lancet September 2009;374(9694):954-955 Free Full Text (Added Sep 29, 2009)

Artemisinin Resistance in Plasmodium falciparum Malaria Arjen M. Dondorp et al. NEJM July 30, 2009;361(5):455-467 Free Full Text (Added Sep 28, 2009)

Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials John J Aponte et al. The Lancet Early o­nline Publication, 17 September 2009doi:10.1016/S0140-6736(09)61258-7 Abstract (Added Sep 18, 2009)

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite Ivo Mueller et al. Lancet Infect Dis September 2009;9(9):555-566 Abstract (Added Sep 17, 2009)

Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity Naresh Sunduru et al.Bioorganic & Medicinal Chemistry September 2009;17(17):6451-6462 Abstract (Added Sep 17, 2009)

Malaria severity status in patients with soil-transmitted helminth infections. Abraham Degarege et al. Acta Tropica October 2009;112(1):8-11 Abstract (Added Sep 17, 2009)

Mobile Phone Based Clinical Microscopy for Global Health Applications. Breslauer DN, Maamari RN, Switz NA, Lam WA, Fletcher DA. PLoS o­nE 2009;4(7): e6320. doi:10.1371/journal.pone.0006320 Free Full Text (Added Aug 27, 2009)

The origin of malignant malaria Stephen M. Rich et al. PNAS www.pnas.org/cgi/doi/10.1073pnas.0907740106 Free Full Text (Added Aug 7, 2009)

Can Prenatal Malaria Exposure Produce an Immune Tolerant Phenotype?: A Prospective Birth Cohort Study in Kenya Indu Malhotra et al. PLoS Med 2009;6(7): e1000116. doi:10.1371/journal.pmed.1000116, Article ID 415953 Free Full Text (Added Aug 5, 2009)

Unraveling the Impact of Malaria Exposure Before Birth Lars Hviid PLoS Med 2009;6(7): e1000117. Free Full Text (Added Aug 5, 2009)

Protection against a Malaria Challenge by Sporozoite Inoculation Meta Roestenberg et al. NEJM. 2009;361(5):468-477. Free Full Text (Added Aug 5, 2009)

Artemisinin Resistance in Plasmodium falciparum Malaria Arjen M. Dondorp et al. NEJM. 2009;361(5):455-467 Free Full Text (Added Aug 5, 2009)

Platelets, Pyrexia, and Plasmodia Doron C. Greenbaum, Garret A. FitzGerald NEJM. 2009;361(5):526-528 Abstract (Added Aug 5, 2009)

A monkey’s tale: The origin of Plasmodium vivax as a human malaria parasite Ananias A. Escalante et al. PNAS. 2005;102(6):1980-85 Free Full Text (Added Aug 5, 2009)

Rapid Diagnosis of Malaria Miguel A SanJoaquin, Clinton K.Murray, Jason W. Bennett Interdisciplinary Perspectives o­n Infectious Diseases. 2009, Article ID 415953, 7 pages doi:10.1155/2009/415953. Free Full Text (Added July 1, 2009)

Comparing Water, Bovine Milk, and Indoor Residual Spraying as Possible Sources of DDT and Pyrethroid Residues in Breast Milk Barbara Sereda, Henk Bouwman, Henrik Kylin ournal of Toxicology and Environmental Health. January 2009 Part A;72(14):897-908 Abstrat (Added July 1, 2009)

Malaria and vitamin A deficiency in African children: a vicious circle? Miguel A SanJoaquin, Malcolm E Molyneux Malaria Journal. 2009;8:134 doi:10.1186/1475-2875-8-134. Free Full Text (Added June 27, 2009)

The effect of mimicking febrile temperature and drug stress o­n malarial development Ratchaneewan Aunpad et al. Annals of Clinical Microbiology and Antimicrobials. 2009;8:19 doi:10.1186/1476-0711-8-19. Free Full Text (Added June 27, 2009)

Risk factors for malaria deaths in Jalpaiguri district, West Bengal, India: evidence for further action Jagannath Sarkar et al. Malaria Journal. 2009;8:133 doi:10.1186/1475-2875-8-133. Free Full Text (Added June 18, 2009)

Malaria Diagnosis: A Brief Review Noppadon Tangpukdee, Chatnapa Duangdee, Polrat Wilairatana, Srivicha Krudsood Korean J Parasitol. 2009 Jun;47(2):93-102. Free Full Text (Added June 16, 2009)

Malarial Hepatopathy in Falciparum Malaria Shahnaz Shah, Liaquat Ali, Rukhsana Abdul Sattar, Tariq Aziz, Tahir Ansari, Jamal Ara Journal of the College of Physicians and Surgeons Pakistan. 2009;19;(6):367-370. Free Full Text (Added June 16, 2009)

Simulation of the cost-effectiveness of malaria vaccines Fabrizio Tediosi et al. Malaria Journal. 2009;8:127 doi:10.1186/1475-2875-8-127 Free Full Text (Added June 16, 2009)

Larvicidal activity of neem oil (Azadirachta indica) formulation against mosquitoes Virendra K Dua et al. Malaria Journal. 2009;8:124 doi:10.1186/1475-2875-8-124 Free Full Text (Added June 16, 2009)

Good News in Malaria Control… Now What? Richard W. Steketee. Am. J. Trop. Med. Hyg. 2009;80(6):879–880. Free Full Text (Added June 9, 2009)

Severe Retinal Whitening in an Adult with Cerebral Malaria. Maude RJ, Hassan MU, Beare NAV. Am. J. Trop. Med. Hyg. 2009;80(6):881. Free Full Text (Added June 9, 2009)

Comparison of Sulfadoxine-Pyrimethamine, Unsupervised Artemether-Lumefantrine, and Unsupervised Artesunate-Amodiaquine Fixed-Dose Formulation for Uncomplicated Plasmodium falciparum Malaria in Benin: A Randomized Effectiveness Noninferiority TrialJean-Franc et al. The Journal of Infectious Diseases 2009; 200:57–65.
Abstract (Added June 9, 2009)

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Rowe JA, Claessens A, Corrigan RA, Arman M. Expert reviews in molecular medicine May 2009; Vol. 11:e16. doi:10.1017/S1462399409001082. Abstract (Added June 9, 2009)

Effect of Malaria Rapid Diagnostic Tests o­n the Management of Uncomplicated Malaria with Artemether-Lumefantrine in Kenya: A Cluster Randomized Trial. Jacek Skarbinski et al. Am. J. Trop. Med. Hyg. 2009;80(6):919-926. Abstract (Added June 9, 2009)

Vivax Malaria: A Major Cause of Morbidity in Early Infancy. Jeanne R. Poespoprodjo et al. Clinical Infectious Diseases 2009;48:1704–1712. Abstract (Added June 9, 2009)

A New Malaria Agent in African Hominids. Ollomo B, Durand P, Prugnolle F, Douzery E, Arnathau C, et al. PLoS Pathog 2009;5(5): e1000446. doi:10.1371/journal.ppat.1000446. Free Full Text (Added June 3, 2009)

Antimalarial natural products of marine and freshwater origin Karl Gademann, Joanna Kobylinska. The Chemical RecordMay 2009. Abstract (Added June 3, 2009)

Malaria Control Insecticide Residues in Breastmilk: The Need to Consider Infant Health Risks Hindrik Bouwman, Henrik Kylin Env Health PerspMay 2009. Free Full Text (Added June 3, 2009)

Strong Gametocytocidal Effect of Methylene Blue-Based Combination Therapy against Falciparum Malaria: A Randomised Controlled Trial. Coulibaly B, Zoungrana A, Mockenhaupt FP, Schirmer RH, Klose C, et al. PLoS o­nE2009;4(5): e5318. doi:10.1371/journal.pone.0005318. Free Full Text (Added June 3, 2009)

Influence of Rapid Malaria Diagnostic Tests o­n Treatment and Health Outcome in Fever Patients, Zanzibar—A Crossover Validation Study Msellem MI, Mårtensson A, Rotllant G, Bhattarai A, Strömberg J, et al. PLoS Med2009;6(4): e1000070. Free Full Text (Added May 5, 2009)

The Role of Rapid Diagnostic Tests in Managing Malaria. Bisoffi Z, Gobbi F, Angheben A, Van den Ende J. PLoS Med. 2009;6(4): e1000063 Free Full Text (Added May 5, 2009)

Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A. Spring MD, Cummings JF, Ockenhouse CF, Dutta S, Reidler R, et al. PLoS o­nE 2009;4(4):e5254
Free Full Text (Added May 5, 2009)

Towards high-throughput molecular detection of Plasmodium: new approaches and molecular markers Steenkeste N, Incardona S, Chy S et al. Malaria Journal2009;8:86. Free Full Text (Added May 5, 2009)

The Malaria Severity Score: a Method for Severity Assessment and Risk Prediction of Hospital Mortality for Falciparum Malaria in Adults MK Mohapatra, SP Das. JAPI. 2009;57:119-126 Free Full Text (Added Feb 10, 2009)

Malarial anemia and STAT6 Robson KJH, Weatherall DJ. Haematologica. 2009;94(2) Free Full Text (Added Feb 10, 2009)

STAT6-mediated suppression of erythropoiesis in an experimental model of malarial anemia Thawani N, Tam M, Stevenson MM. Haematologica. 2009;94(2):195-204 Free Full Text (Added Feb 10, 2009)

Probability of emergence of antimalarial resistance in different stages of the parasite life cycle Wirichada Pongtavornpinyo et al. Journal compilation. 2009;52–61 Free Full Text (Added Feb 10, 2009)

Malarial Retinopathy in Cerebral Malaria Beare NAV, Glover SJ, Molyneux M. Am. J. Trop. Med. Hyg. 2009;80(2):171 Free Full Text (Added Feb 10, 2009)

Methemoglobinemia and Adverse Events in Plasmodium vivax Malaria Patients Associated with High Doses of Primaquine Treatment Jaime Carmona-Fonseca, Gonzalo Álvarez, Amanda Maestre. Am. J. Trop. Med. Hyg. 2009;80(2):188-193. Abstract (Added Feb 10, 2008)

Severe Plasmodium vivax Malaria: A Report o­n Serial Cases from Bikaner in Northwestern India Kochar DK et al. Am. J. Trop. Med. Hyg. 2009;80(2):194-198 Abstract (Added Feb 10, 2009)

Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review PrayGod G, De Frey A, Eisenhut M. Malaria Journal. 2008, 7:210 Free Full Text (Added Oct 28, 2008)

Comparative genomics of the neglected human malaria parasite Plasmodium vivax Carlton JM et al. Nature. 455, 757-763 (9 October 2008) Free Full Text (Added Oct 24, 2008)

Malaria research in the post-genomic era Winzeler EA. Nature. 455, 751-756 (9 October 2008) Abstract (Added Oct 24, 2008)

Burden of Cerebral Malaria in Central India (2004–2007) Jain V et al. Am. J. Trop. Med. Hyg. 2008;79(4):636-642. Abstract (Added Oct 24, 2008)

Biological control of mosquito populations through frogs: Opportunities & constrains Raghavendra K, Sharma P, Dash AP. Indian J Med Res . 2008;128:22-25 Free Full Text (Added Oct 8, 2008)

Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: A report from three study sites in sub-Saharan Africa Ajayi IO et al. Malaria Journal. 2008, 7:190(37) Free Full Text (Added Oct 8, 2008)

Neurosyphilis, Malaria, and the Discovery of Antipsychotic Agents Frankenburg FR,  Baldessarini RJ. Harvard Review of Psychiatry. 2008;16(5):299-307(37) Abstract (Added Oct 8, 2008)

Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum. Park Y, Diez-Silva M, Popescu G et al. PNAS. 2008;105(37) Free Full Text (Added Sep 10, 2008)

Platelet Factor 4 Mediates Inflammation in Experimental Cerebral Malaria. Srivastava K, Cockburn IA, Swaim A et al. Cell Host & Microbe. 2008;4(2):179-187 Abstract (Added Aug 21, 2008)

Presumptive treatment of fever cases as malaria: Help or hindrance for malaria control? Roly D Gosling, Christopher J Drakeley, Alex Mwita, Daniel Chandramohan. Malaria Journal. 2008, 7:132 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-132.pdf (Added Jul 28, 2008)

The usefulness of a new rapid diagnostic test, the First Response® Malaria Combo (pLDH/HRP2) card test, for malaria diagnosis in the forested belt of central India Praveen K Bharti, Nipun Silawat, Pushpendra P Singh, Mrigendra P Singh1, Manmohan Shukla, Gyan Chand, Aditya P Dash, Neeru Singh. Malaria Journal. 2008, 7:126 Full Text at
http://www.malariajournal.com/content/pdf/1475-2875-7-126.pdf (Added Jul 28, 2008)

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. Lucy C Okell1, Chris J Drakeley, Azra C Ghani, Teun Bousema, Colin J Sutherland. Malaria Journal. 2008, 7:125 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-125.pdf (Added Jul 28, 2008)

Plasmodium falciparum in ancient Egypt. [letter]. Nerlich AG, Schraut B, Dittrich S, Jelinek T, Zink AR. Emerg Infect Dis [serial o­n the Internet]. 2008 Aug Full Text at http://www.cdc.gov/EID/content/14/8/1317.htm (Added Jul 28, 2008)

Cerebral Malaria in Children Is Associated With Long-term Cognitive Impairment. John CC, MD, Bangirana P, Byarugaba J et al. PEDIATRICS. Vol. 122 No. 1 July 2008, pp. e92-e99 Full Text at http://pediatrics.aappublications.org/cgi/content/full/122/1/e92 (Added Jul 14, 2008)

Evaluation of light microscopy and rapid diagnostic test for the detection of malaria under operational field conditions: a household survey in Ethiopia. Endeshaw T, Gebre T, Ngondi J et al. Malaria Journal. 2008;7:118 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-118.pdf (Added Jul 14, 2008)

First Case of Emergence of Atovaquone-Proguanil (MalaroneTM) Resistance in Plasmodium falciparum During Treatment in Traveller from Comoros. Savini H, Bogreau H, Bertaux L et al. Antimicrob. Agents Chemother. doi:10.1128/AAC.00282-08 Abstract at http://aac.asm.org/cgi/content/abstract/AAC.00282-08v1 (Added Apr 29, 2008)

Qinghaosu (Artemisinin): The Price of Success White NJ. Science 2008;320(5874):330-334 Abstract at http://www.sciencemag.org/cgi/content/abstract/320/5874/330 (Added Apr 29, 2008)

A Malaria Fingerprint in the Human Genome? Daily JP, Sabeti P. NEJM Apr 16, 2008 Full text at http://content.nejm.org/cgi/content/full/NEJMe0801414 (Added Apr 22, 2008)

A magneto-optic route towards the in-vivo diagnosis of malaria: preliminary results and pre-clinical trial data Newman DM, Heptinstall J, Matelon RJ et al. Biophys J Apr 2008. Full text athttp://www.biophysj.org/cgi/rapidpdf/biophysj.107.128140v1 (Added Apr 22, 2008)

Adverse Pregnancy Outcomes in an Area Where Multidrug-Resistant Plasmodium vivax and Plasmodium falciparum Infections Are Endemic Poespoprodjo JR, Fobia W,Kenangalem E et al. Clinical Infectious Diseases 2008;46:1374–1381 Abstract at http://www.journals.uchicago.edu/doi/abs/10.1086/586743 (Added Apr 22, 2008)

Dihydroartemisinin—Piperaquine Rescue Treatment of Multidrug-resistant Plasmodium falciparum Malaria in Pregnancy: A Preliminary Report Rijken MJ, McGready R, Boel ME et al. Am. J. Trop. Med. Hyg. 2008;78(4):543-545 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/4/543 (Added Apr 22, 2008)

Malaria: progress, perils, and prospects for eradication Greenwood BM, Fidock DA, Kyle DE et al. J. Clin. Invest. 2008;118(4):1266-1276 Full Text at http://www.jci.org/articles/view/33996 (Added Apr 22, 2008)

Malaria Vector Management: Where Have We Come From and Where Are We Headed? Muturi EJ, Burgess P, Novak RJ.Am. J. Trop. Med. Hyg. 2008;78(4):536–537. Full Text at http://www.ajtmh.org/cgi/reprint/78/4/536 (Added Apr 22, 2008)

Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda. Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon, Chi Phan. Malaria Journal 2008;7:49 Full Text at http://www.malariajournal.com/content/pdf/1475-2875-7-49.pdf

Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues Andrews KT, Tran TN, Lucke AJ et al. Antimicrobial Agents and Chemotherapy. 2008;52(4):1454-1461. Abstract at http://aac.asm.org/cgi/content/abstract/52/4/1454

Inhibition of Efflux of Quinolines as New Therapeutic Strategy in Malaria Maud H, Sandrine A, Christophe R, Jacques B, Bruno P. Current Topics in Medicinal Chemistry. 2008;8(7):563-578(16) Abstract at http://www.ingentaconnect.com/content/ben/ctmc/2008/00000008/00000007/art00003

Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies. Melba Gomes, Isabela Ribeiro1, Marian Warsame, Harin Karunajeewa, Max Petzold. BMC Infectious Diseases 2008;8:39 Full Text available at http://www.biomedcentral.com/content/pdf/1471-2334-8-39.pdf

Plasmodium-Induced Inflammation by Uric Acid. Orengo JM, Evans JE, Bettiol E, Leliwa-Sytek A, Day K, et al. PLoS Pathog 2008;4(3): e1000013. doi:10.1371/journal.ppat.1000013 Full Text available at http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1000013

The Alpha-Carbonic Anhydrase from the Malaria Parasite and its Inhibition. Jerapan K, Supuran CT. Current Pharmaceutical Design. 2008;14(7):631-640. Abstract available at http://www.ingentaconnect.com/content/ben/cpd/2008/00000014/00000007/art00005

Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda. Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon, Chi Phan. Malaria Journal 2008;7:49 doi:10.1186/1475-2875-7-49. Full Text Available at http://www.malariajournal.com/content/pdf/1475-2875-7-49.pdf

Increased Plasmodium falciparum Gametocyte Production in Mixed Infections with P. malariae. J. Teun Bousema, Chris J. Drakeley, Petra F. Mens, Theo Arens, Rein Houben, Sabah A. Omar, Louis C. Gouagna, Henk Schallig, Robert W. Sauerwein. Am. J. Trop. Med. Hyg. 2008;78(3):442-448 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/442?etoc

Malaria in Pregnancy in the Solomon Islands: Barriers to Prevention and Control. Bridget Appleyard, Makiva Tuni, Qin Cheng, Nanhua Chen, Joan Bryan, James S. McCarthy. Am. J. Trop. Med. Hyg. 2008;78(3):449-454 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/449?etoc

Geographical Distribution of Amino Acid Mutations in Plasmodium vivax DHFR and DHPS from Malaria Endemic Areas of Thailand. Kanchana Rungsihirunrat, Carol Hopkins Sibley, Mathirut Mungthin, Kesara Na-Bangchang. Am. J. Trop. Med. Hyg. 2008;78(3):462-467 Abstract at http://www.ajtmh.org/cgi/content/abstract/78/3/462?etoc

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